A Bibliometric and Visualized Analysis of Cardiac Regeneration Over a 20-Year Period

被引:10
|
作者
Ma, Siyuan [1 ]
Yan, Junyu [1 ]
Chen, Lu [1 ]
Zhu, Yingqi [1 ]
Chen, Kaitong [1 ]
Zheng, Cankun [1 ]
Shen, Mengjia [1 ]
Liao, Yulin [1 ]
机构
[1] Southern Med Univ, Guangdong Prov Key Lab Shock & Microcirculat, Natl Clin Res Ctr Kidney Dis,Nanfang Hosp, Dept Cardiol,Guangdong Prov Inst Nephrol,State Ke, Guangzhou, Peoples R China
来源
基金
中国国家自然科学基金;
关键词
cardiac regeneration; bibliometric analysis; cardiomyocyte proliferation; induced pluripotent stem cell; extracellular vesicles; direct cardiac reprogramming; macrophages; microRNAs; ACUTE MYOCARDIAL-INFARCTION; LEFT-VENTRICULAR FUNCTION; CARDIOSPHERE-DERIVED CELLS; BONE-MARROW-CELLS; ISCHEMIC CARDIOMYOPATHY; STEM-CELLS; HEART REGENERATION; PROGENITOR CELLS; TRANSPLANTATION; CARDIOMYOCYTES;
D O I
10.3389/fcvm.2021.789503
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background: Recent research has suggested that cardiac regeneration may have the widely applicable potential of treating heart failure (HF). A comprehensive understanding of the development status of this field is conducive to its development. However, no bibliometric analysis has summarized this field properly. We aimed to analyze cardiac regeneration-related literature over 20 years and provide valuable insights.Methods: Publications were collected from the Web of Science Core Collection (WoSCC). Microsoft Excel, VOSviewer, CiteSpace, and alluvial generator were used to analyze and present the data.Results: The collected 11,700 publications showed an annually increasing trend. The United States and Harvard University were the leading force among all the countries and institutions. The majority of articles were published in Circulation Research, and Circulation was the most co-cited journal. According to co-citation analysis, burst detection and alluvial flow map, cardiomyocyte proliferation, stem cells, such as first-and second-generation, extracellular vesicles especially exosomes, direct cardiac reprogramming, macrophages, microRNAs, and inflammation have become more and more popular recently.Conclusions: Cardiac regeneration remains a research hotspot and develops rapidly. How to modify cardiac regeneration endogenously and exogenously may still be the hotspot in the future and should be discussed more deeply.
引用
收藏
页数:16
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