Measurement of fluid viscosity based on droplet microfluidics

被引:19
|
作者
Zeng, Wen [1 ]
Fu, Hai [1 ]
机构
[1] Harbin Inst Technol, Dept Fluid Control & Automat, Harbin 150001, Peoples R China
基金
中国国家自然科学基金; 中国博士后科学基金;
关键词
BLOOD;
D O I
10.1063/5.0002929
中图分类号
O3 [力学];
学科分类号
08 ; 0801 ;
摘要
We demonstrate an efficient method that can precisely measure the viscosity of fluids based on droplet microfluidics. For our design of the droplet microfluidic viscometer, the volume of the fluid sample required for testing the fluid viscosity is on the order of nanoliters. In particular, a T-junction microdroplet generator is designed for the production of monodisperse droplets, and the flow rates of the continuous and dispersed phases are controlled by the pressure-driven microfluidic device. By giving a specified viscosity of the dispersed phase, the viscosity of the continuous phase can be measured, while considering the linear relation between the droplet length and the flow-rate ratio of the two phases, the linear relation between the droplet length and the viscosity ratio of the two phases can be obtained. For our design of the T-junction microdroplet generator, the viscosity ratio of the two phases can be predicted by testing the length of droplets formed in the microchannel, and therefore, the fluid viscosity of the continuous phase can be calculated. More importantly, the comparison between the measured and the given viscosity of the continuous phase is provided for three different geometries of the T-junctions, and consequently, the testing precision of the fluid viscosity can be validated experimentally.
引用
收藏
页数:6
相关论文
共 50 条
  • [21] Droplet-based microfluidics for microtoxicological studies
    Cao, Jialan
    Koehler, Johann Michael
    ENGINEERING IN LIFE SCIENCES, 2015, 15 (03): : 306 - 317
  • [22] Protein crystallization research based on droplet microfluidics
    Wu X.
    Jiang X.
    Zhang Y.
    Lyu H.
    Huang F.
    Yu X.
    Huagong Jinzhan/Chemical Industry and Engineering Progress, 2023, 42 (04): : 2024 - 2030
  • [23] Sample Preparation for Droplet-Based Microfluidics
    Huang, Juinn-Dar
    Liu, Chia-Hung
    2014 14TH INTERNATIONAL SYMPOSIUM ON INTEGRATED CIRCUITS (ISIC), 2014, : 364 - 367
  • [24] Droplet-based microfluidics in biomedical applications
    Amirifar, Leyla
    Besanjideh, Mohsen
    Nasiri, Rohollah
    Shamloo, Amir
    Nasrollahi, Fatemeh
    de Barros, Natan Roberto
    Davoodi, Elham
    Erdem, Ahmet
    Mahmoodi, Mahboobeh
    Hosseini, Vahid
    Montazerian, Hossein
    Jahangiry, Jamileh
    Darabi, Mohammad Ali
    Haghniaz, Reihaneh
    Dokmeci, Mehmet R.
    Annabi, Nasim
    Ahadian, Samad
    Khademhosseini, Ali
    BIOFABRICATION, 2022, 14 (02)
  • [25] Digital microfluidics: Droplet based logic gates
    Cheow, Lih Feng
    Yobas, Levent
    Kwong, Dim-Lee
    APPLIED PHYSICS LETTERS, 2007, 90 (05)
  • [26] Droplet based microfluidics integrated with machine learning
    Srikanth, Sangam
    Dubey, Satish Kumar
    Javed, Arshad
    Goel, Sanket
    SENSORS AND ACTUATORS A-PHYSICAL, 2021, 332
  • [27] Enhancement of mixing by droplet-based microfluidics
    Fowler, J
    Moon, HJ
    Kim, CJ
    FIFTEENTH IEEE INTERNATIONAL CONFERENCE ON MICRO ELECTRO MECHANICAL SYSTEMS, TECHNICAL DIGEST, 2002, : 97 - 100
  • [28] Droplet-based microfluidics at the femtolitre scale
    Leman, Marie
    Abouakil, Faris
    Griffiths, Andrew D.
    Tabeling, Patrick
    LAB ON A CHIP, 2015, 15 (03) : 753 - 765
  • [29] Droplet-Based Microfluidics: Applications in Pharmaceuticals
    Trinh, Thi Ngoc Diep
    Do, Hoang Dang Khoa
    Nam, Nguyen Nhat
    Dan, Thach Thi
    Trinh, Kieu The Loan
    Lee, Nae Yoon
    PHARMACEUTICALS, 2023, 16 (07)
  • [30] Droplet Microfluidics for Chip-Based Diagnostics
    Kaler, Karan V. I. S.
    Prakash, Ravi
    SENSORS, 2014, 14 (12) : 23283 - 23306