Synthetic utility of enaminonitrile moiety in heterocyclic synthesis

被引：0

作者：

Madkour, H. M. F. ^{[1
,2
]}

Afify, A. A. E. ^{[2
]}

Elsayed, G. A. ^{[2
]}

Salem, M. S. ^{[2
]}

机构：

[1] Balochistan Univ, Inst Biochem, Quetta, Pakistan

[2] Ain Shams Univ, Fac Sci, Dept Chem, Synthet Organ Chem Lab, Cairo, Egypt

来源：

BULGARIAN CHEMICAL COMMUNICATIONS | 2008年 / 40卷 / 02期

关键词：

enaminonitrile; 4H-chromene; chromenopyrimidine; chromenotetrazolopyrimidine; antimicrobial activity;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

2-Amino-7-hydroxy-4-(3,4-dimethoxyphenyl)-4H-chromene-3-carbonitrile has been synthesized and utilized to construct a variety of new heterocyclic systems such as. chromenopyrimidines, chromeno-oxazinone, chromenotriazolo-pyrimidinethiones, oxopyrazole derivative, chromenotetrazolopyrimidine via reactions with phenyl isothiocyanate, hydrazine hydrate in ethanol at room and refluxing temperatures, formamide and carbon disulfide in ethanolic potassium hydroxide and pyridine respectively. Some of the synthesized compounds have been found potent as antifungal and antibacterial.

引用

页码：147 / 159

页数：13

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