RETRACTED: A new In(III) coordination polymer: Crystal structure, clinical and nursing value for ovarian cancer treatment (Retracted Article)

被引：0
|
作者：
Meng, Zhaoxia [1 ]
Xu, Zhiqin [1 ]
Li, Dan [2 ]
机构：
[1] Cangzhou Med Coll, Nursing Dept, Cangzhou 061001, Peoples R China
[2] Cangzhou Peoples Hosp, Gynaecol Dept, Cangzhou 061000, Peoples R China
来源：
JOURNAL OF THE INDIAN CHEMICAL SOCIETY | 2021年 / 98卷 / 11期
关键词：
Coordination polymer; Ovarian cancer; CCK-8; assay; PERFORMANCE; FE; CO;
D O I：
10.1016/j.jics.2021.100198
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
In the p resent study, a novel 3-dimensional coordination polymer (CP) has been produced in success under solvothermal conditions and it was characterized through TGA, EA, FTIR spectroscopy, the diffraction of singlecrystal X-ray and PXRD, and its chemical formula is (Me2NH2)3[In3(TATAT)2](DMF)11 (1, TATAT is 5,5',5 ''(1,3,5-triazine-2,4,6-triyl)tris(azanediyl)triisophthalate). The clinical and nursing value of the new compound for ovarian cancer treatment was investigated and the specific mechanism was examined as well. First of all, the compound's inhibitory activity against the ovarian cancer viability was determined through the CCK-8 assay, and the toxicity of the new compound was also evaluated. In addition to this, the real time RT-PCR was further conducted and the estrogen receptor relative expression on ovarian cancer cells was measured.
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页数：5
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