Ultrasensitive and Highly Selective Detection of Testosterone Using a Surface Plasmon Resonance Sensor Combined with Molecularly Imprinted Films

被引:12
|
作者
Wei, Qingquan [1 ]
Wei, Tianxin [1 ]
Wu, Xiaoguang [1 ]
机构
[1] Beijing Inst Technol, Minist Educ, Key Lab Cluster Sci, Beijing 100081, Peoples R China
基金
中国国家自然科学基金;
关键词
AMINO-ACIDS; POLYMER; SERUM; STEROIDS;
D O I
10.1246/cl.2011.132
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
An ultrasensitive and highly selective testosterone detection method by surface plasmon resonance (SPR) combined with molecularly imprinted films (MTFs) was developed. The coupling angle shifts were highly selective to testosterone and showed a linear relationship to the logarithmic concentrations (from 10(-15) to 10(-10) mol L-1) of the testosterone in the acetonitrile. The selectivity of the thin testosterone-imprinted films was examined by 10(-4) mol L-1 progesterone acetonitrile solution, no observable binding was detected.
引用
收藏
页码:132 / 133
页数:2
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