Muscular vasculitis confined to lower limbs: description of two case reports and a review of the literature

被引:14
|
作者
Tripoli, Alessandra [1 ]
Barsotti, Simone [1 ,2 ]
Pollina, Luca Emanuele [3 ]
Della Rossa, Alessandra [1 ]
Neri, Rossella [1 ]
d'Ascanio, Anna [1 ]
Baldini, Chiara [1 ]
Mosca, Marta [1 ]
机构
[1] Univ Pisa, Dept Clin & Expt Med, Rheumatol Unit, Via Roma 67, I-56126 Pisa, Italy
[2] Univ Siena, Dept Med Biotechnol, Siena, Italy
[3] Univ Pisa, Med Sch Hosp, Dept Pathol, Pisa, Italy
关键词
Vasculitis; Polyarteritis nodosa; Muscle; Muscular MRI; Muscular biopsy; Myositis; POLYARTERITIS-NODOSA; MUSCLE INVOLVEMENT; MYOSITIS; MRI;
D O I
10.1007/s00296-017-3841-z
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Muscular involvement is common during systemic vasculitides, such as polyarteritis nodosa. However, in rare cases, muscular involvement can be the only clinically evident feature of the disease. The clinical pattern of isolated muscular vasculitis may mimic several other inflammatory muscle disorders, such as idiopathic inflammatory myositis, and may represent a challenge in differential diagnosis. Herewith, we present two clinical cases as examples of peculiar clinical and histopathological characteristics of isolated muscular vasculitis. Our patients were successfully treated with steroids and immunosuppressive agents. Moreover, we provide a review of the recent existing medical literature. Our cases suggest the importance of performing muscle biopsy in patients with muscular symptoms to guide the diagnosis and the treatment.
引用
收藏
页码:2115 / 2121
页数:7
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