Ultrasound Findings in Fetal Congenital Heart Block Associated With Maternal Anti-Ro/SSA and Anti-La/SSB Antibodies

被引:5
|
作者
Lai, Jasmine [1 ]
Clark, Toshi J. [2 ]
Tan, Justin H. [3 ]
Delaney, Shani [1 ]
Jolley, Jennifer A. [1 ]
机构
[1] Univ Washington, Med Ctr, Dept Obstet & Gynecol, Div Maternal Fetal Med, Seattle, WA 98195 USA
[2] Univ Washington, Med Ctr, Dept Radiol, Div Body Imaging, Seattle, WA 98195 USA
[3] Univ Calif San Diego, San Diego Med Ctr, Dept Radiol, San Diego, CA 92103 USA
关键词
fetal congenital heart block; neonatal lupus erythematosus; fetal bradyarrhythmia; NEONATAL LUPUS; CARDIAC MANIFESTATIONS; ATRIOVENTRICULAR-BLOCK; RECURRENCE RATES; RISK; HYDROXYCHLOROQUINE; MORBIDITY; MORTALITY; REGISTRY;
D O I
10.1097/RUQ.0000000000000112
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
We present the sonographic features of a second-trimester fetus diagnosed with a bradyarrhythmia at 19 weeks' gestation. The mother carried a diagnosis of Sjogren syndrome, including the presence of SSA and SSB antibodies. Ultrasound M-mode and fetal echocardiogram revealed the etiology of the bradycardia to be a complete fetal congenital heart block, likely due to transplacental passage of autoimmune anti-Ro/SSA and anti-La/SSB antibodies. Consequential to the congenital heart block, the fetus developed hydrops fetalis at 21 weeks' gestational age. We discuss the 2 major etiologies of congenital heart block and the implications in subsequent pregnancies.
引用
收藏
页码:34 / 36
页数:3
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