Updated Pathway to Micro-elimination of Hepatitis C Virus in the Hemodialysis Population

被引:2
|
作者
Rajasekaran, Arun [1 ]
Franco, Ricardo A. [2 ]
Overton, Edgar T. [2 ]
McGuire, Brendan M. [3 ]
Towns, Graham C. [1 ]
Locke, Jayme E. [4 ]
Sawinski, Deirdre L. [5 ]
Bell, Emmy K. [1 ]
机构
[1] Univ Alabama Birmingham, Dept Med, Div Nephrol, Birmingham, AL 35294 USA
[2] Univ Alabama Birmingham, Dept Med, Div Infect Dis, Birmingham, AL 35294 USA
[3] Univ Alabama Birmingham, Dept Med, Div Gastroenterol & Hepatol, Birmingham, AL 35294 USA
[4] Univ Alabama Birmingham, Dept Med & Surg, Comprehens Transplant Inst, Birmingham, AL USA
[5] Univ Penn, Renal Electrolyte & Hypertens Div, Perelman Sch Med, Philadelphia, PA 19104 USA
来源
KIDNEY INTERNATIONAL REPORTS | 2021年 / 6卷 / 07期
关键词
diagnosis; hemodialysis; HCV; hepatitis C virus; kidney transplantation; micro-elimination; transmission; treatment; HEALTH-CARE WORKERS; SUSTAINED VIROLOGICAL RESPONSE; RISK-FACTORS; EXTRAHEPATIC MANIFESTATIONS; UNITED-STATES; INFECTION; TRANSMISSION; OUTBREAK; PREVALENCE; DIALYSIS;
D O I
10.1016/j.ekir.2021.04.015
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Chronic hepatitis C virus (HCV) infection continues to be transmitted to hemodialysis (HD) patients within HD facilities globally. The goal of the World Health Organization to micro-eliminate HCV infection from the HD population by the year 2030 is not on target to be achieved. Obstacles to eliminate HCV in HD settings remain daunting due to a complex system created by a confluence of guidelines, legislation, regulation, and economics. HCV prevalence remains high and seroconversion continues among the HD patient population globally as a result of the HD procedure. Preventive strategies that effectively prevent HCV transmission, treatment-as-prevention, and rapid referral to treatment balanced with kidney transplant candidacy should be added to the current universal precautions approach. A safer system must be designed before HCV transmission can be halted and eliminated from the HD population.
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页码:1788 / 1798
页数:11
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