Effect of Amoxicillin and Clavulanate Potassium Combined with Bazhengsan on Pediatric Urinary Tract Infection

被引:0
|
作者
Zhang, Shengjun [1 ]
Wang, Zhenghua [2 ]
Xu, Guoping [3 ]
机构
[1] Peoples Hosp Rizhao, Dept Pediat Surg, Rizhao 276826, Shandong, Peoples R China
[2] Rizhao Maternal & Child Hlth Care Hosp, Dept Surg, Rizhao 276800, Shandong, Peoples R China
[3] Wuhan Xinzhou Dist Peoples Hosp, Dept Urol & Anorectol, Wuhan 430400, Hubei, Peoples R China
关键词
D O I
10.1155/2021/4575503
中图分类号
R [医药、卫生];
学科分类号
10 ;
摘要
Objective. To explore the therapeutic effect of amoxicillin and clavulanate potassium combined with Bazhengsan on pediatric urinary tract infection (UTI). Methods. The data of 120 UTI children treated in Wuhan Xinzhou District People's Hospital from February 2019 to February 2020 were retrospectively analyzed. They were equally split into experimental group (EG) and control group (CG) according to the order of admission. All children were treated with amoxicillin and clavulanate potassium for suspension (twice a day), and EG was additionally treated with one dose of Bazhengsan daily. Both groups were treated for 10 days. After treatment, the immune function indexes, inflammatory factor levels, and clinical efficacy were compared before and after treatment. Results. No remarkable differences in the general data such as blood routine and urine routine results were observed between the two groups before treatment (P > 0.05). After treatment, EG achieved obviously better immune function indexes (P < 0.001) and lower levels of inflammatory factors (P < 0.05) compared with CG. Besides, the treatment effective rate in EG (96.7%) was higher than that in CG (P < 0.05). Conclusion. Amoxicillin and clavulanate potassium combined with Bazhengsan can improve the immune function of UTI children and reduce the levels of inflammatory factors, with remarkable effects, which should be popularized in practice.
引用
收藏
页数:7
相关论文
共 50 条
  • [1] AMOXICILLIN CLAVULANATE IN URINARY-TRACT INFECTION
    GASSER, TC
    LARSEN, EH
    MADSEN, PO
    [J]. UROLOGY, 1987, 29 (01) : 111 - 114
  • [2] PHARMACOKINETICS OF POTASSIUM CLAVULANATE IN COMBINATION WITH AMOXICILLIN IN PEDIATRIC-PATIENTS
    NELSON, JD
    KUSMIESZ, H
    SHELTON, S
    [J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1982, 21 (04) : 681 - 682
  • [3] Clinical Effect, Analysis of Amoxicillin Clavulanate Potassium Combined with Shenling Baizhu Powder in the Treatment of Gastric Ulcer with Helicobacter pylori Infection
    Wang, Ying
    Hou, Shu
    [J]. INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2022, 84 : 131 - 135
  • [4] Dosing of amoxicillin/clavulanate for treatment of lower respiratory tract infection - Reply
    Calver, A
    Walsh, N
    Baran, C
    Lonergan, V
    Quinn, P
    Singh, KP
    Orzolek, W
    [J]. CLINICAL INFECTIOUS DISEASES, 1998, 26 (02) : 529 - 530
  • [5] Lymphocutaneous nocardia Brasiliensis infection:: A pediatric case cured with amoxicillin/clavulanate
    Nolt, D
    Wadowsky, RM
    Green, M
    [J]. PEDIATRIC INFECTIOUS DISEASE JOURNAL, 2000, 19 (10) : 1023 - 1025
  • [6] Effect and Safety of Amoxicillin-Clavulanate Potassium and Ceftriaxone Combined with Pulmonary Physical Therapy on Neonatal Pneumonia
    Li, Jing
    Zhang, Di
    Yao, Wenxiu
    [J]. INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 85 (04) : 264 - 269
  • [7] Pediatric Urinary Tract Infection
    Heffner, Viday A.
    Gorelick, Marc H.
    [J]. CLINICAL PEDIATRIC EMERGENCY MEDICINE, 2008, 9 (04) : 233 - 237
  • [8] Pediatric urinary tract infection
    Santen, SA
    Altieri, MF
    [J]. EMERGENCY MEDICINE CLINICS OF NORTH AMERICA, 2001, 19 (03) : 675 - +
  • [9] EFFECT OF CLAVULANIC ACID ON INACTIVATED AMOXICILLIN EXCRETION IN URINARY-TRACT INFECTION
    MIYAZAKI, K
    ISEKI, K
    ISHIZAWA, T
    ARITA, T
    SAKAI, S
    KUMAMOTO, Y
    [J]. CLINICAL PHARMACOLOGY & THERAPEUTICS, 1985, 37 (05) : 508 - 511
  • [10] Urinary angiotensinogen in pediatric urinary tract infection
    Mayumi, Reina
    Murano, Yayoi
    Yokota, Reina
    Nakao, Akihiro
    Miyazaki, Nao
    Hara, Taichi
    Mizotani, Akira
    Hayashi, Kuniyoshi
    Sakurai, Yumiko
    Shoji, Hiromichi
    Nakazawa, Tomoyuki
    Shimizu, Toshiaki
    [J]. PEDIATRICS INTERNATIONAL, 2019, 61 (07) : 712 - 714