The synthesis of several chiral phosphorus reagents and their application in the asymmetric addition of aromatic aldehydes to diethylzinc

被引：0
|
作者：
Yang, ZH [1 ]
Zhou, ZH [1 ]
Tang, C [1 ]
机构：
[1] Nankai Univ, Inst Elementoorgan Chem, State Key Lab Elementoorgan Chem, Tianjin 300071, Peoples R China
来源：
MAIN GROUP METAL CHEMISTRY | 2001年 / 24卷 / 06期
关键词：
D O I：
暂无
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
Six chiral phosphorus compounds were synthesized by the reaction of (-)alpha -phenylethylamine, L- prolinol, (S)-binaphthol, and psi-(-)-ephedrine with various phosphoryl reagents respectively, and used in the asymmetric addition of aromatic aldehydes with diethylzinc as catalyst. The corresponding aromatic secalcohols were obtained in good chemical yield with enantiometric excesses varing from low to moderate.
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页码：379 / 382
页数：4
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