Beyond ocrelizumab in primary progressive multiple sclerosis

被引:0
|
作者
Williams, Thomas [1 ]
Chataway, Jeremy [1 ,2 ]
机构
[1] UCL, Fac Brain Sci, UCL Queen Sq Inst Neurol, Queen Sq Multiple Sclerosis Ctr,Dept Neuroinflamm, London, England
[2] Univ Coll London Hosp, Biomed Res Ctr, Natl Inst Hlth Res, London, England
基金
英国医学研究理事会;
关键词
THERAPY;
D O I
10.1038/s41582-022-00724-8
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Currently, the anti-CD20 monoclonal antibody ocrelizumab is the only approved treatment for primary progressive multiple sclerosis (PPMS). However, a new study suggests that other immunomodulatory disease-modifying therapies that are often used to treat relapsing forms of multiple sclerosis could be effective in people with PPMS who have evidence of active inflammatory disease.
引用
收藏
页码:641 / 642
页数:2
相关论文
共 50 条
  • [31] Real world experience with ocrelizumab in patients with primary progressive multiple sclerosis
    Lopez Ruiz, R.
    Dotor Garcia-Soto, J.
    Hiraldo, J. D. G.
    Ruiz-Pena, J. L.
    Paramo Camino, M. D.
    Ruiz De Arcos, M.
    Navarro Mascarell, G.
    Eichau Madueno, S.
    [J]. MULTIPLE SCLEROSIS JOURNAL, 2020, 26 (3_SUPPL) : 301 - 302
  • [32] SOCIOECONOMIC VALUE OF OCRELIZUMAB IN THE TREATMENT OF PATIENTS WITH PRIMARY PROGRESSIVE MULTIPLE SCLEROSIS
    Di Maio, D.
    Liu, C.
    Marcelli, G.
    Alvarez, Sanchez J.
    Overell, J.
    [J]. VALUE IN HEALTH, 2020, 23 : S632 - S633
  • [33] Real-World Results of Ocrelizumab Treatment for Primary Progressive Multiple Sclerosis
    Daniels, K.
    van der Nat, P. B.
    Frequin, S. T. F. M.
    van der Wees, P. J.
    Biesma, D. H.
    Hoogervorst, E. L. J.
    van de Garde, E. M. W.
    [J]. MULTIPLE SCLEROSIS INTERNATIONAL, 2020, 2020
  • [34] Effect of Ocrelizumab on Thalamic Atrophy in Patients with Relapsing and Primary Progressive Multiple Sclerosis
    Arnold, Douglas L.
    Sprenger, Till
    Bar-Or, Amit
    Wolinsky, Jerry S.
    Kappos, Ludwig
    Kolind, Shannon
    Manfrini, Marianna
    Magon, Stefano
    van Beek, Johan
    Koendgen, Harold
    Bernasconi, Corrado
    Gaetano, Laura
    Traboulsee, Anthony
    [J]. NEUROLOGY, 2020, 94 (15)
  • [35] Ocrelizumab Extended Interval Dosing in Primary Progressive Multiple Sclerosis: An Italian Experience
    Zanghi, Aurora
    Ferraro, Diana
    Callari, Graziella
    Valentino, Paola
    Granella, Franco
    Patti, Francesco
    Lus, Giacomo
    Bonavita, Simona
    Moretti, Maria Claudia
    Avolio, Carlo
    D'Amico, Emanuele
    [J]. CURRENT NEUROPHARMACOLOGY, 2024, 22 (02) : 339 - 345
  • [36] Primary progressive multiple sclerosis to be treated with ocrelizumab: a mistaken case of cobalamin deficiency
    Feldman, Sydney
    Aljarallah, Salman
    Saidha, Shiv
    [J]. BMJ CASE REPORTS, 2019, 12 (05)
  • [37] Monoclonal antibody ocrelizumab for primary-progressive multiple sclerosis in adults: a systematic review
    Klabukova, D.
    Davydovskaya, M.
    Ermolaeva, T.
    Holownia-Voloskova, M.
    Polyakova, K.
    Fisun, A.
    [J]. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 2019, 75 : S32 - S32
  • [38] Impact of ocrelizumab on reducing more severe disability progression in primary progressive multiple sclerosis
    Kappos, L.
    Giovannoni, G.
    de Seze, J.
    Montalban, X.
    Wolinsky, J.
    Belachew, S.
    Deol-Bhullar, G.
    Han, J.
    Julian, L.
    Hauser, S. L.
    [J]. EUROPEAN JOURNAL OF NEUROLOGY, 2017, 24 : 44 - 44
  • [39] Ocrelizumab in people with primary progressive multiple sclerosis: A real-world multicentric study
    Skoric, Magdalena Krbot
    Kes, Vanja Basic
    Grbic, Nevena
    Lazibat, Ines
    Pavelin, Sanda
    Zubonja, Tea Mirosevic
    Komso, Milica
    Piskac, Spomenka Kidemet
    Abicic, Ana
    Piskac, Dominik
    Adamec, Ivan
    Barun, Barbara
    Gabelic, Tereza
    Habek, Mario
    [J]. MULTIPLE SCLEROSIS AND RELATED DISORDERS, 2024, 89
  • [40] Relapsing-remitting and primary progressive multiple sclerosis treated with ocrelizumab: A comparative study
    de Antonio, Luis A. Rodriguez
    Cuberta-Gonzalez, Ines
    Garcia-Castanon, Inmaculada
    Oreja-Guevara, Celia
    [J]. MULTIPLE SCLEROSIS AND RELATED DISORDERS, 2023, 69