Pyrrolopyrrole aza-BODIPY near-infrared photosensitizer for dual-mode imaging-guided photothermal cancer therapy

被引：45

作者：

Wu, Chaolong ^{[1
,2
]}

Huang, Xiaoyu ^{[1
,2
]}

Tang, Yunyun ^{[1
,2
]}

Xiao, Wanyue ^{[1
,2
]}

Sun, Liguo ^{[3
]}

Shao, Jinjun ^{[1
,2
]}

Dong, Xiaochen ^{[1
,2
]}

机构：

[1] Nanjing Tech Univ NanjingTech, Key Lab Flexible Elect KLOFE, Nanjing 211800, Jiangsu, Peoples R China

[2] Nanjing Tech Univ NanjingTech, IAM, Nanjing 211800, Jiangsu, Peoples R China

[3] Binzhou Med Univ Hosp, Dept Radiol, Yantai 264100, Shangdong, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2019年 / 55卷 / 06期

关键词：

ORGANIC-DYE; TUMOR; NANOPARTICLES; AGENT; ABSORPTION; NANOSHEETS; RELEASE; MOS2;

D O I：

10.1039/c8cc07768a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A NIR photosensitizer pyrrolopyrrole aza-BODIPY (PPAB) was synthesized in a straightforward manner. Through the use of PPAB NPs as a photothermal agent, photoacoustic imaging (PAI) and NIR fluorescence imaging (NIR-FI) can be achieved in vivo. In addition, the photothermal ablation of tumor cells can be realized both in vitro and in vivo, even at a low concentration (0.5 mg kg(-1)).

引用

页码：790 / 793

页数：4

共 50 条

[41] Near-infrared upper phenyl-fused BODIPY as a photosensitizer for photothermal-photodynamic therapy
Yu, Tao
Zhang, Dongxiang
Wang, Jie
Sun, Changliang
Cui, Tianfang
Xu, Zhangrun
Jiang, Xin-Dong
Du, Jianjun
[J]. Journal of Materials Chemistry B, 2022, 10 (16) : 3048 - 3054
[42] Tetraphenylethylene- and fluorene-functionalized near-infrared aza-BODIPY dyes for living cell imaging
Zhu, Li
Xie, Wensheng
Zhao, Lingyun
Zhang, Yongjie
Chen, Zhijian
[J]. RSC ADVANCES, 2017, 7 (88): : 55839 - 55845
[43] Theranostic Colloidal Nanoparticles of Pyrrolopyrrole Cyanine Derivatives for Simultaneous Near-Infrared Fluorescence Cancer Imaging and Photothermal Therapy
Huang, Shuo
Liu, Wei
Huang, Jing
Wang, Xiaochen
Yang, Cangjie
Bohra, Hassan
Liu, Quan
Wang, Mingfeng
[J]. ACS APPLIED BIO MATERIALS, 2018, 1 (04): : 1109 - 1117
[44] A novel Met-IR-782 near-infrared probe for fluorescent imaging-guided photothermal therapy in breast cancer
Wu, Yang
Zhang, Wei
Xu, Di
Ding, Li
Ma, Rong
Wu, Jian-Zhong
Tang, Jin-Hai
[J]. LASERS IN MEDICAL SCIENCE, 2018, 33 (07) : 1601 - 1608
[45] Theranostic Nanomedicine Carrying L-Menthol and Near-Infrared Dye for Multimodal Imaging-Guided Photothermal Therapy of Cancer
Zhang, Chunyang
Liu, Jie
Guo, Huanling
Wang, Wei
Xu, Ming
Tan, Yang
Huang, Tongyi
Cao, Zhong
Shuai, Xintao
Xie, Xiaoyan
[J]. Advanced Healthcare Materials, 2019, 8 (16):
[46] A novel Met-IR-782 near-infrared probe for fluorescent imaging-guided photothermal therapy in breast cancer
Yang Wu
Wei Zhang
Di Xu
Li Ding
Rong Ma
Jian-Zhong Wu
Jin-Hai Tang
[J]. Lasers in Medical Science, 2018, 33 : 1601 - 1608
[47] A novel near-infrared colorimetric and fluorescent probe based on a piperidine-substituted aza-BODIPY photosensitizer for detection of extreme acidity
Zhou, Jinfeng
Li, Gang
Ling, Jiejie
Zhou, Qing
Chu, Chunjie
[J]. ANALYTICAL METHODS, 2021, 13 (36) : 4099 - 4104
[48] γ-Glutamyl transpeptidase-activatable near-infrared nanoassembly for tumor fluorescence imaging-guided photothermal therapy
Zhou, Fangyuan
Yang, Shikui
Zhao, Chao
Liu, Wangwang
Yao, Xufeng
Yu, Hui
Sun, Xiaolian
Liu, Yi
[J]. THERANOSTICS, 2021, 11 (14): : 7045 - 7056
[49] Near-Infrared Fluorescence/Photoacoustic Agent with an Intensifying Optical Performance for Imaging-Guided Effective Photothermal Therapy
Ye, Fengying
Huang, Weijing
Li, Chonglu
Li, Guangjin
Yang, Wen-Chao
Liu, Sheng Hua
Yin, Jun
Sun, Yao
Yang, Guang-Fu
[J]. ADVANCED THERAPEUTICS, 2020, 3 (12)
[50] A near-infrared fluorescent aza-bodipy probe for dual-wavelength detection of hydrogen peroxide in living cells
Xu, Jingjing
Zhai, Jingying
Xu, Yanmei
Zhu, Jingwei
Qin, Yu
Jiang, Dechen
[J]. ANALYST, 2016, 141 (08) : 2380 - 2383

← 1 2 3 4 5 →