Light-Activated CO Donor as a Universal CO Surrogate for Pd- Catalyzed and Light-Mediated Carbonylation

被引：12

作者：

de la Cruz, Ladie Kimberly ^{[1
]}

Bauer, Nicola ^{[1
]}

Cachuela, Alyssa ^{[1
]}

Tam, Wing Sze ^{[2
]}

Tripathi, Ravi ^{[1
]}

Yang, Xiaoxiao ^{[1
]}

Wang, Binghe ^{[1
]}

机构：

[1] Georgia State Univ, Ctr Diagnost & Therapeut, Dept Chem, Atlanta, GA 30303 USA

[2] Hong Kong Baptist Univ, Kowloon Tong, Hong Kong, Peoples R China

来源：

ORGANIC LETTERS | 2022年 / 24卷 / 27期

基金：

美国国家卫生研究院;

关键词：

CROSS-COUPLING REACTIONS; CARBON-MONOXIDE SOURCE; ARYL BROMIDES; ATMOSPHERIC-PRESSURE; PALLADIUM CATALYST; SITU GENERATION; FORMIC-ACID; PARAFORMALDEHYDE; DERIVATIVES; PHOTOCORMS;

D O I：

10.1021/acs.orglett.2c01726

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A low-molecular-weight, solid CO surrogate that only requires a low-power LED for activation to release 2 equiv of CO is reported. The surrogate can be universally implemented in various palladium-catalyzed carbonylative transformations. It is also compatible with protocols that employ blue-light to activate conventionally inaccessible substrates such as nonactivated alkyl halides. Furthermore, we demonstrate that the photolabile CO releasing scaffold can be installed into polymeric materials, thereby creating new materials with CO-releasing capabilities.

引用

页码：4902 / 4907

页数：6