Ni(II)-catalyzed conia-ene reaction of 1,3-dicarbonyl compounds with alkynes

被引：97
|
作者：
Gao, Q [1 ]
Zheng, BF [1 ]
Li, JH [1 ]
Yang, D [1 ]
机构：
[1] Univ Hong Kong, Dept Chem, Hong Kong, Hong Kong, Peoples R China
来源：
ORGANIC LETTERS | 2005年 / 7卷 / 11期
关键词：
D O I：
10.1021/ol050532q
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
We have discovered a Ni(II)-catalyzed Conia-ene reaction of 1,3-dicarbonyl compounds with alkynes. In the presence of Ni(acac)(2) and Yb(OTf)(3), various acetylenic 1,3-dicarbonyl compounds underwent Conia-ene reaction to give mono- and bicyclic olefinic cyclopentanes. A mechanism involving the enol-yne-Ni complex formation is proposed and supported by deuterium-labeling experiments.
引用
收藏
页码：2185 / 2188
页数：4
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