Integrated Epigenetic and Transcriptional Single Cell Analysis of t(11;14) Myeloma and Its BCL2 Dependency

被引:0
|
作者
Leblay, Noemie
Ahn, Sungwoo
Maity, Ranjan
Lee, Holly
Barakat, Ellie
Bahlis, Nizar J.
Neri, Paola
机构
关键词
D O I
10.1182/blood-2021-152993
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
725
引用
收藏
页数:3
相关论文
共 50 条
  • [1] Integrated epigenetic and transcriptional single-cell analysis of t(11;14) multiple myeloma and its BCL2 dependency
    Leblay, Noemie
    Ahn, Sungwoo
    Tilmont, Remi
    Poorebrahim, Mansour
    Maity, Ranjan
    Lee, Holly
    Barakat, Elie
    Alberge, Jean -Baptiste
    Sinha, Sarthak
    Jaffer, Arzina
    Barwick, Benjamin G.
    Boise, Lawrence H.
    Bahlis, Nizar
    Neri, Paola
    BLOOD, 2024, 143 (01) : 42 - 56
  • [2] Variable BCL2/BCL2L1 ratio in multiple myeloma with t(11;14)
    Cleynen, Alice
    Samur, Mehmet
    Perrot, Aurore
    Buisson, Laure
    Maheo, Sabrina
    Fulciniti, Mariateresa
    Attal, Michel
    Munshi, Nikhil
    Avet-Loiseau, Herve
    Corre, Jill
    BLOOD, 2018, 132 (26) : 2778 - 2780
  • [3] Advances in precision therapy with venetoclax in multiple myeloma with t(11;14) and high BCL2 expression: A systematic review.
    Ahmed, Zahoor
    Nabeel, Shaha
    Farooqui, Arafat Ali
    Imtiaz, Hassan
    Ashraf, Aqsa
    Farooq, Umer
    Din, Mohammad Ammad Ud
    Wahab, Ahsan
    Rehman, Saif ur
    Anwer, Faiz
    JOURNAL OF CLINICAL ONCOLOGY, 2020, 38 (15)
  • [4] Venetoclax in upfront induction therapy for primary plasma cell leukemia with t(11;14) or BCL2 expression
    Roy, Tina
    An, Joseph B.
    Doucette, Kimberly
    Chappell, Aimee M.
    Vesole, David H.
    LEUKEMIA & LYMPHOMA, 2022, 63 (03) : 759 - 761
  • [5] Pseudonegative BCL2 protein expression in a t(14;18) translocation positive lymphoma cell line: a need for an alternative BCL2 antibody
    Masir, Noraidah
    Campbell, Lisa J.
    Jones, Margaret
    Mason, David Y.
    PATHOLOGY, 2010, 42 (03) : 212 - 216
  • [6] Multiple myeloma with t(11;14)-associated immature phenotype has lower CD38 expression and higher BCL2 dependence
    Kitadate, Akihiro
    Terao, Toshiki
    Narita, Kentaro
    Ikeda, Sho
    Takahashi, Yuto
    Tsushima, Takafumi
    Miura, Daisuke
    Takeuchi, Masami
    Takahashi, Naoto
    Matsue, Kosei
    CANCER SCIENCE, 2021, 112 (09) : 3645 - 3654
  • [7] Direct Transcriptional Repression of BCL2 by BCL6 in Germinal Centre B Cells and Its Disruption in B Cell Lymphomas with BCL2 Locus Alterations
    Piovan, Erich
    Saito, Masumichi
    Basso, Katia
    Novak, Urban
    Shen, Qiong
    Pasqualucci, Laura
    Dalla-Favera, Riccardo
    BLOOD, 2008, 112 (11) : 115 - 116
  • [8] Clinical significance of the t(14;18) and BCL2 overexpression in follicular large cell lymphoma
    Weisenburger, DD
    Gascoyne, RD
    Bierman, PJ
    Shenkier, T
    Horsman, DE
    Lynch, JC
    Chan, WC
    Greiner, TC
    Connors, JM
    Vose, JM
    Armitage, JO
    Sanger, WG
    LEUKEMIA & LYMPHOMA, 2000, 36 (5-6) : 513 - 523
  • [9] Translocation t(14;18) and gain of chromosome 18/BCL2:: effects on BCL2 expression and apoptosis in B-cell non-Hodgkin's lymphomas
    Galteland, E
    Sivertsen, EA
    Svendsrud, DH
    Smedshammer, L
    Kresse, SH
    Meza-Zepeda, LA
    Myklebost, O
    Suo, Z
    Mu, D
    DeAngelis, PM
    Stokke, T
    LEUKEMIA, 2005, 19 (12) : 2313 - 2323
  • [10] Translocation t(14;18) and gain of chromosome 18/BCL2: effects on BCL2 expression and apoptosis in B-cell non-Hodgkin's lymphomas
    E Galteland
    E A Sivertsen
    D H Svendsrud
    L Smedshammer
    S H Kresse
    L A Meza-Zepeda
    O Myklebost
    Z Suo
    D Mu
    P M DeAngelis
    T Stokke
    Leukemia, 2005, 19 : 2313 - 2323