OATP1B1 in vitro inhibition assay enrichment & QSAR modeling

被引:0
|
作者
Danielson, Matthew [1 ]
机构
[1] Eli Lilly & Co, Indianapolis, IN 46285 USA
关键词
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
P169
引用
收藏
页码:107 / 107
页数:1
相关论文
共 50 条
  • [31] Evaluating the In Vitro Inhibition of UGT1A1, OATP1B1, OATP1B3, MRP2, and BSEP in Predicting Drug-Induced Hyperbilirubinemia
    Chang, Jae H.
    Plise, Emile
    Cheong, Jonathan
    Ho, Quynh
    Lin, Molly
    MOLECULAR PHARMACEUTICS, 2013, 10 (08) : 3067 - 3075
  • [32] Interaction of Sulfonylureas with Liver Uptake Transporters OATP1B1 and OATP1B3
    Chen, Yu
    Chen, Lin
    Zhang, Hong
    Huang, Shibo
    Xiong, Yuqing
    Xia, Chunhua
    BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2018, 123 (02) : 147 - 154
  • [33] PROPOSAL OF PARAMETER FOR SCREENING OF OATP1B1 INHIBITION AT EARLY DRUG DISCOVERY STAGE
    Murata, Hiroyuki
    Ito, Soichiro
    Nomura, Yukihiro
    Kogayu, Motohiro
    DRUG METABOLISM AND PHARMACOKINETICS, 2017, 32 (01) : S103 - S103
  • [34] Proposal of a Parameter for OATP1B1 Inhibition Screening at the Early Drug Discovery Stage
    Murata, Hiroyuki
    Ito, Soichiro
    Kusuhara, Hiroyuki
    Nomura, Yukihiro
    Taniguchi, Toshio
    JOURNAL OF PHARMACEUTICAL SCIENCES, 2019, 108 (12) : 3898 - 3902
  • [35] Construction of HEK293 cells stably expressing wild-type organic anion transporting polypeptide 1B1 (OATP1B1☆1a) and variant OATP1B1☆1b and OATP1B1☆15
    Chen, M.
    Qu, B. X.
    Chen, X. L.
    Hu, H. H.
    Jiang, H. D.
    Yu, L. S.
    Zhou, Q.
    Zeng, S.
    PHARMAZIE, 2016, 71 (06): : 337 - 339
  • [36] Effect of clotrimazole on transport mediated by human OATP1B1 and OATP1B3
    Gui, Chunshan
    Thompson, Lucas
    Hagenbuch, Bruno
    HEPATOLOGY, 2006, 44 (04) : 379A - 379A
  • [37] The Effect of Single Nucleotide Variations in the Transmembrane Domain of OATP1B1 on in vitro Functionality
    Kiander, Wilma
    Vellonen, Kati-Sisko
    Malinen, Melina M.
    Gynther, Mikko
    Hagstrom, Marja
    Bhattacharya, Madhushree
    Auriola, Seppo
    Koenderink, Jan B.
    Kidron, Heidi
    PHARMACEUTICAL RESEARCH, 2021, 38 (10) : 1663 - 1675
  • [38] OATP1B1 Polymorphism as a Determinant of Erythromycin Disposition
    Lancaster, C. S.
    Bruun, G. H.
    Peer, C. J.
    Mikkelsen, T. S.
    Corydon, T. J.
    Gibson, A. A.
    Hu, S.
    Orwick, S. J.
    Mathijssen, R. H. J.
    Figg, W. D.
    Baker, S. D.
    Sparreboom, A.
    CLINICAL PHARMACOLOGY & THERAPEUTICS, 2012, 92 (05) : 642 - 650
  • [39] Application of LC-MS/MS Method for Evaluating Rosuvastatin Affinity with OATP1B1 and OATP2B1 in vitro
    Zhang, Zhi-Yu
    Li, Quan-Sheng
    Si, Duan-Yun
    Yi, Xiu-Lin
    Liu, Chang-Xiao
    ASIAN JOURNAL OF CHEMISTRY, 2014, 26 (02) : 335 - 341
  • [40] The Effect of Single Nucleotide Variations in the Transmembrane Domain of OATP1B1 on in vitro Functionality
    Wilma Kiander
    Kati-Sisko Vellonen
    Melina M. Malinen
    Mikko Gynther
    Marja Hagström
    Madhushree Bhattacharya
    Seppo Auriola
    Jan B. Koenderink
    Heidi Kidron
    Pharmaceutical Research, 2021, 38 : 1663 - 1675