Frailty in kidney transplantation: a review on its evaluation, variation and long-term impact

被引:9
|
作者
Alfieri, Carlo [1 ,2 ]
Malvica, Silvia [1 ]
Cesari, Matteo [2 ,3 ]
Vettoretti, Simone [1 ]
Benedetti, Matteo [1 ]
Cicero, Elisa [1 ]
Miglio, Roberta [1 ]
Caldiroli, Lara [1 ]
Perna, Alessandro [4 ]
Cervesato, Angela [4 ]
Castellano, Giuseppe [1 ,2 ]
机构
[1] Fdn IRCCS Ca Granda Osped Policlin Mila, Dept Nephrol Dialysis & Renal Transplantat, Milan, Italy
[2] Univ Milan, Dept Clin Sci & Community Hlth, Milan, Italy
[3] IRCCS Ist Clin Sci Maugeri, Geriatr Unit, Milan, Italy
[4] Univ Campania L Vanvitelli, Dept Translat Med Sci, Naples, Italy
关键词
chronic kidney disease; frailty; graft survival; renal transplantation; STAGE RENAL-DISEASE; SCREENING INSTRUMENTS; MORTALITY; HEALTH; PREVALENCE; DISABILITY; INJURY; INDEX; TIME;
D O I
10.1093/ckj/sfac149
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
The problem of frailty in kidney transplantation is an increasingly discussed topic in the transplant field, partially also generated by the multiple comorbidities by which these patients are affected. The criteria currently used to establish the presence and degree of frailty can be rapidly assessed in clinical practice, even in patients with chronic kidney disease (CKD). The main objectives of this work are: (i) to describe the method of evaluation and the impact that frailty has in patients affected by CKD, (ii) to explore how frailty should be studied in the pre-transplant evaluation, (iii) how frailty changes after a transplant and (iv) the impact frailty has over the long term on the survival of renal transplant patients.
引用
收藏
页码:2020 / 2026
页数:7
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