Purine derivatives as potent BTK inhibitors for autoimmune diseases

被引:0
|
作者
Shi, Qing [1 ]
Liu, Chunjian [1 ]
Lin, James [1 ]
Dyckman, Alaric J. [1 ]
Li, Hedy [1 ]
Vandevier, Lauren E. [1 ]
Cavallaro, Cullen [1 ]
Spergel, Steven [1 ]
Burke, James R. [1 ]
Tebben, Andrew [1 ]
Strnad, Joann [1 ]
Surti, Neha [1 ]
Muckelbauer, Jodi K. [1 ]
Mcintyre, Kim [1 ]
Leftheris, Katerina [1 ]
Carter, Percy H. [1 ]
Tino, Joseph [1 ]
Delucca, George V. [1 ]
机构
[1] Bristol Myers Squibb Co, New York, NY 10154 USA
关键词
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
316-MEDI
引用
收藏
页数:1
相关论文
共 50 条
  • [1] Purine derivatives as potent Bruton's tyrosine kinase (BTK) inhibitors for autoimmune diseases
    Shi, Qing
    Tebben, Andrew
    Dyckman, Alaric J.
    Li, Hedy
    Liu, Chunjian
    Lin, James
    Spergel, Steve
    Burke, James R.
    McIntyre, Kim W.
    Olini, Gilbert C.
    Strnad, Joann
    Surti, Neha
    Muckelbauer, Jodi K.
    Chang, Chiehying
    An, Yongmi
    Cheng, Lin
    Ruan, Qian
    Leftheris, Katerina
    Carter, Percy H.
    Tino, Joseph
    De Lucca, George V.
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 24 (09) : 2206 - 2211
  • [2] Nicotinamide derivatives as potent BTK inhibitors for autoimmune diseases
    De Lucca, George V.
    Shi, Qing
    Liu, Chunjian
    Tebben, Andrew
    Strnad, Joann
    Surti, Neha
    Muckelbauer, Jodi K.
    Mcintyre, Kim
    Burke, James R.
    Leftheris, Katerina
    Carter, Percy H.
    Tino, Joseph
    Chang, Chiehying
    [J]. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2011, 242
  • [3] Recent Advances in BTK Inhibitors for the Treatment of Inflammatory and Autoimmune Diseases
    Zhang, Datong
    Gong, He
    Meng, Fancui
    [J]. MOLECULES, 2021, 26 (16):
  • [4] Clinical Research Progress of BTK Inhibitors in the Treatment of Autoimmune Diseases
    Lin, Pei
    Zhang, Dandan
    Lin, Jun
    [J]. CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2023, 23 (28) : 2609 - 2620
  • [5] Discovery of pyrazolopyrimidine derivatives as potent BTK inhibitors with effective anticancer activity in MCL
    Ran, Fansheng
    Liu, Yang
    Liu, Meixia
    Zhang, Daoguang
    Wang, Peng
    Dong, Junze
    Tang, Wendi
    Zhao, Guisen
    [J]. BIOORGANIC CHEMISTRY, 2019, 89
  • [6] Development of potent inhibitors of a critical mediator of autoimmune and inflammatory diseases
    Al-Abed, Yousef
    Cheng, Kai Fan
    Dabideen, Darrin
    Ochani, Mahendar
    Aljabari, Bayan
    Pavlov, Valentin A.
    Lolis, Elias
    Miller, Edmund J.
    [J]. DRUGS OF THE FUTURE, 2007, 32 : 27 - 27
  • [7] Potent and selective pyridone BTK inhibitors with activity against mutant forms of BTK
    Crawford, James
    [J]. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2015, 249
  • [8] Pyrrolidinone Derivatives as NIK Inhibitors for Treating Autoimmune and Inflammatory Diseases
    Sabnis, Ram W.
    [J]. ACS MEDICINAL CHEMISTRY LETTERS, 2024, 15 (05): : 581 - 582
  • [9] Pyrrolidinone Derivatives as NIK Inhibitors for Treating Inflammatory and Autoimmune Diseases
    Sabnis, Ram W.
    [J]. ACS MEDICINAL CHEMISTRY LETTERS, 2024, 15 (03): : 322 - 323
  • [10] Purine derivatives as potent γ-secretase modulators
    Rivkin, Alexey
    Ahearn, Sean P.
    Chichetti, Stephanie M.
    Hamblett, Christopher L.
    Garcia, Yudith
    Martinez, Michelle
    Hubbs, Jed L.
    Reutershan, Michael H.
    Daniels, Matthew H.
    Siliphaivanh, Phieng
    Otte, Karin M.
    Li, Chaomin
    Rosenau, Andrew
    Surdi, Laura M.
    Jung, Joon
    Hughes, Bethany L.
    Crispino, Jamie L.
    Nikov, George N.
    Middleton, Richard E.
    Moxham, Christopher M.
    Szewczak, Alexander A.
    Shah, Sanjiv
    Moy, Lily Y.
    Kenific, Candia M.
    Tanga, Flobert
    Cruz, Jonathan C.
    Andrade, Paula
    Angagaw, Minilik H.
    Shomer, Nirah H.
    Miller, Thomas
    Munoz, Benito
    Shearman, Mark S.
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2010, 20 (07) : 2279 - 2282