ERA 223: A phase III trial of radium-223 (Ra-223) in combination with abiraterone acetate and prednisone/prednisolone for the treatment of asymptomatic or mildly symptomatic chemotherapy-naive patients (pts) with bone-predominant metastatic castration-resistant prostate cancer (mCRPC)

被引:0
|
作者
Smith, M. R. [1 ]
Parker, C. C. [2 ]
Saad, F. [3 ]
Miller, K. [4 ]
Tombal, B. [5 ]
Ng, Q. S. [6 ]
Boegemann, M. [7 ]
Matveev, V. [8 ]
Piulats, J. M. [9 ]
Zucca, L. E. [10 ]
Heidenreich, A. [11 ]
Kakehi, Y. [12 ]
Zhang, A. [13 ]
Krissel, H. [14 ]
Shen, J. [15 ]
Wagner, V. [16 ]
Higano, C. [17 ,18 ]
机构
[1] Massachusetts Gen Hosp, Dept Oncol, Boston, MA 02114 USA
[2] Royal Marsden NHS Fdn Trust, Dept Urol, Inst Canc Res, Sutton, Surrey, England
[3] Univ Montreal Hosp Ctr, Dept Urol, Montreal, PQ, Canada
[4] Charite, Dept Med Oncol, Berlin, Germany
[5] Clin Univ St Luc, Dept Urol, Brussels, Belgium
[6] Natl Canc Ctr Singapore, Div Med Oncol, Singapore, Singapore
[7] Univ Munster, Med Ctr, Dept Clin Oncol Urol, Munster, Germany
[8] NN Blokhin Canc Res Ctr, Dept Urol, Moscow, Russia
[9] Catalan Canc Inst, Dept Med Oncol, Barcelona, Spain
[10] Barretos Canc Hosp, Dept Med Oncol, Barretos, Brazil
[11] Univ Hosp Cologne, Dept Urol, Cologne, Germany
[12] Kagawa Univ, Dept Urol, Takamatsu, Kagawa, Japan
[13] Bayer HealthCare Pharmaceut, Oncol, Whippany, NJ USA
[14] Bayer AG, Oncol, Berlin, Germany
[15] Bayer HealthCare Pharmaceut, Clin Stat, Whippany, NJ USA
[16] Bayer Consumer Care AG, Oncol, Basel, Switzerland
[17] Univ Washington, Dept Med Oncol, Seattle, WA 98195 USA
[18] Fred Hutchinson Canc Res Ctr, 1124 Columbia St, Seattle, WA 98104 USA
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
LBA30
引用
收藏
页数:1
相关论文
共 50 条
  • [31] Clinical outcomes of a Dutch prospective observational registry of metastatic castration resistant prostate cancer (mCRPC) patients treated with radium-223 (Ra-223).
    Louhanepessy, Rebecca
    Badrising, Sushil
    van der Noort, Vincent
    Coenen, Jules L. L. M.
    Hamberg, Paul
    Beeker, Aart
    Wagenaar, Nils
    Lam, Marnix G. E. H.
    Celik, Filiz
    Loosveld, Olaf
    Oostdijk, Ad
    Zuetenhorst, Johanna Maria
    Vegt, Erik
    Zwart, Wilbert
    Bergman, Andre M.
    JOURNAL OF CLINICAL ONCOLOGY, 2019, 37 (07)
  • [32] Prognostic role of inflammatory biomarkers from peripheral blood and clinical factors in metastatic castration-resistant prostate cancer (mCRPC) patients (pts) treated with radium-223 (Ra-223) (BIO-Ra-223 study).
    Rebuzzi, Sara Elena
    Bauckneht, Matteo
    Signori, Alessio
    Frantellizzi, Viviana
    Rizzini, Elisa Lodi
    Mascia, Manlio
    Lavelli, Valentina
    Stazza, Maria Lina
    Licari, Maria
    Donegani, Maria Isabella
    Ponzano, Marta
    Cavallini, Letizia
    Laghi, Viola
    Cindolo, Luca
    Costa, Renato Patrizio
    Spanu, Angela
    Rubini, Giuseppe
    Monari, Fabio
    De Vincentis, Giuseppe
    Fornarini, Giuseppe
    JOURNAL OF CLINICAL ONCOLOGY, 2021, 39 (15)
  • [33] Real-world utilization of radium-223 (Ra-223) for the treatment of metastatic castration-resistant prostate cancer (mCRPC): A US tertiary oncology center analysis
    McKay, Rana R.
    Silver, Rebecca
    Bhak, Rachel
    Korves, Caroline
    Cheng, Mu
    Appukkuttan, Sreevalsa
    Simmons, Stacey J.
    Duh, Mei Sheng
    Taplin, Mary-Ellen
    JOURNAL OF CLINICAL ONCOLOGY, 2020, 38 (06)
  • [34] A randomized, double-blind, comparison of radium-223 and placebo, in combination with abiraterone acetate and prednisolone, in castration-resistant metastatic prostate cancer: subgroup analysis of Japanese patients in the ERA 223 study
    Nobuaki Matsubara
    Go Kimura
    Hiroji Uemura
    Hirotsugu Uemura
    Motonobu Nakamura
    Satoshi Nagamori
    Atsushi Mizokami
    Hiroaki Kikukawa
    Makoto Hosono
    Seigo Kinuya
    Heiko Krissel
    Jonathan Siegel
    Yoshiyuki Kakehi
    International Journal of Clinical Oncology, 2020, 25 : 720 - 731
  • [35] A randomized, double-blind, comparison of radium-223 and placebo, in combination with abiraterone acetate and prednisolone, in castration-resistant metastatic prostate cancer: subgroup analysis of Japanese patients in the ERA 223 study
    Matsubara, Nobuaki
    Kimura, Go
    Uemura, Hiroji
    Uemura, Hirotsugu
    Nakamura, Motonobu
    Nagamori, Satoshi
    Mizokami, Atsushi
    Kikukawa, Hiroaki
    Hosono, Makoto
    Kinuya, Seigo
    Krissel, Heiko
    Siegel, Jonathan
    Kakehi, Yoshiyuki
    INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY, 2020, 25 (04) : 720 - 731
  • [36] Alkaline phosphatase (ALP) decline and overall survival (OS) in patients (pts) with metastatic castration-resistant prostate cancer (mCRPC) treated with radium-223 (Ra-223) in the REASSURE study.
    James, Nicholas D.
    Heinrich, Daniel
    Castro, Elena
    George, Saby
    Song, Daniel Y.
    Dizdarevic, Sabina
    Baldari, Sergio
    Essler, Markus
    De Jong, Igle Jan
    Lastoria, Secondo
    Hammerer, Peter G.
    Meltzer, Jeffrey
    Sandstrom, Per
    Verholen, Frank
    Tombal, Bertrand F.
    O'Sullivan, Joe M.
    Sartor, A. Oliver
    JOURNAL OF CLINICAL ONCOLOGY, 2022, 40 (16)
  • [37] Fractionated docetaxel and radium-223 (Ra223) in metastatic castration-resistant prostate cancer (CRPC): A phase I trial.
    Connell, Brendan James
    Folefac, Edmund
    Hwang, Clara
    Lawlor, Christian
    Mathew, Paul
    JOURNAL OF CLINICAL ONCOLOGY, 2021, 39 (06)
  • [38] UTILIZATION OF RADIUM-223 DICHLORIDE (RA-223) IN PATIENTS WITH METASTATIC CASTRATION-RESISTANT PROSTATE CANCER IN CANADA: A REAL-WORLD RETROSPECTIVE STUDY
    Lapierre, M.
    Fraelic, A.
    VALUE IN HEALTH, 2016, 19 (03) : A162 - A162
  • [39] Pain analysis from the phase III randomized ALSYMPCA study with radium-223 dichloride (Ra-223) in patients with castration-resistant prostate cancer (CRPC) with bone metastases
    Nilsson, Sten
    Sartor, A. Oliver
    Bruland, Oyvind S.
    Fang, Fang
    Aksnes, Anne-Kirsti
    Parker, Chris
    JOURNAL OF CLINICAL ONCOLOGY, 2013, 31 (06)
  • [40] Hematologic Safety Profile of Radium-223 Dichloride (Ra-223) From the Phase 3 ALSYMPCA Trial in Castration-Resistant Prostate Cancer (CRPC) Patients With Bone Metastases
    Widmark, A.
    Helle, S. I.
    James, N.
    Larsson, A.
    Staudacher, K.
    Haugen, I.
    Garcia-Vargas, J.
    Nilsson, S.
    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2013, 40 : S189 - S190