Live Demonstration: Sample-to-Answer Nucleic Acid Testing Device for Point-of-Care Applications

被引：0

作者：

Choi, Gihoon ^{[1
]}

Guan, Weihua ^{[1
,2
]}

机构：

[1] Penn State Univ, Dept Elect Engn, University Pk, PA 16802 USA

[2] Penn State Univ, Dept Biomed Engn, University Pk, PA 16802 USA

来源：

2019 IEEE SENSORS | 2019年

关键词：

Nucleic acid tests; point-of-care; malaria; non-centrifugal; lab-on-a-disc;

D O I：

10.1109/sensors43011.2019.8956936

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

We demonstrate a sample-to-answer nucleic acid testing device. The streamlined nucleic acid sample processing, including DNA extraction, amplification, and real-time detection, are achieved on a single microfluidic reagent disc by actuating the DNA-carrying magnetic beads against stationary reagent droplets. The battery-powered handheld instrument is unprecedentedly integrated with mechanical, thermal and optical subsystems with data connectivity. LCD touchscreen and smartphone connectivity offer a user-friendly interface for easy operation. This versatile platform can be widely disseminated to a variety of other situations that demand portability, connectivity, and ease-of-use.

引用

页数：1

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