Evolution of antimicrobial resistance of Acinetobacter baumannii in a university hospital

被引：14
|
作者：
Viana, G. F. [1 ]
dos Santos Saalfeld, S. M. [1 ]
Garcia, L. B. [1 ]
Cardoso, C. L. [1 ]
Pelisson, M. [2 ]
Tognim, M. C. B. [1 ]
机构：
[1] Univ Estadual Maringa, Dept Basic Hlth Sci, Maringa, Parana, Brazil
[2] Univ Estadual Londrina, Dept Pathol Clin Analyses & Toxicol, Londrina, Parana, Brazil
来源：
LETTERS IN APPLIED MICROBIOLOGY | 2011年 / 53卷 / 03期
关键词：
Acinetobacter baumannii; epidemiology; genotyping; nosocomial infections; resistance; SUSCEPTIBILITY; TIGECYCLINE; EMERGENCE;
D O I：
10.1111/j.1472-765X.2011.03109.x
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Aims: To investigate the susceptibility pattern and the molecular epidemiology of Acinetobacter baumannii isolates in two periods (1994-1996 and 2004-2007) in Londrina University Hospital. Methods and Results: Antimicrobial susceptibility of 150 A. baumannii isolates was assessed by disc diffusion and agar dilution methods. Genetic similarity amongst the isolates was evaluated by ERIC-PCR. Resistance of A. baumannii to carbapenems increased from 2% (1994-1996) to 73% (2004-2007). Thirty-eight clones were detected. Conclusions: The results of the study suggest that the high prevalence of carbapenem resistance amongst Acinetobacter baumannii organisms in this institution is not caused by the spread of a predominant clone. Significance and Impact of the Study: This work reinforces the importance monitoring antimicrobial susceptibility rates.
引用
收藏
页码：374 / 378
页数：5
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