A phase I trial of the human double minute 2 (HDM2) inhibitor MK-8242 in patients (pts) with advanced solid tumors.

被引：0
|
作者：
Wagner, Andrew J.
Banerji, Udai
Mahipal, Amit
Somaiah, Neeta
Hirsch, Heather Anne
Fancourt, Craig
Levonas, Amy
Lam, Raymond
Meister, Amy
Kemp, Ramon Karmel
Knox, Clayton
Rose, Shelonitda
Hong, David S.
机构：
[1] Dana Farber Canc Inst, Boston, MA 02115 USA
[2] Inst Canc Res, London SW3 6JB, England
[3] Royal Marsden NHS Fdn Trust, London, England
[4] H Lee Moffitt Canc Ctr & Res Inst, Tampa, FL USA
[5] Univ Texas MD Anderson Canc Ctr, Dept Sarcoma Med Oncol, Houston, TX 77030 USA
[6] Merck & Co Inc, Kenilworth, NJ USA
[7] Univ Texas MD Anderson Canc Ctr, Dept Invest Canc Therapeut, Phase Program 1, Houston, TX 77030 USA
来源：
JOURNAL OF CLINICAL ONCOLOGY | 2015年 / 33卷 / 15期
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
10564
引用
收藏
页数：1
相关论文
共 50 条
  • [11] A phase I study of the HDM2 antagonist SAR405838 combined with the MEK inhibitor pimasertib in patients with advanced solid tumours
    Vincent A. de Weger
    Maja de Jonge
    Marlies H. G. Langenberg
    Jan H. M. Schellens
    Martijn Lolkema
    Andrea Varga
    Brigitte Demers
    Koruth Thomas
    Karl Hsu
    Gilles Tuffal
    Samantha Goodstal
    Sandrine Macé
    Eric Deutsch
    British Journal of Cancer, 2019, 120 : 286 - 293
  • [12] A phase I study of the HDM2 antagonist SAR405838 combined with the MEK inhibitor pimasertib in patients with advanced solid tumours
    de Weger, Vincent A.
    de Jonge, Maja
    Langenberg, Marlies H. G.
    Schellens, Jan H. M.
    Lolkema, Martijn
    Varga, Andrea
    Demers, Brigitte
    Thomas, Koruth
    Hsu, Karl
    Tuffal, Gilles
    Goodstal, Samantha
    Mace, Sandrine
    Deutsch, Eric
    BRITISH JOURNAL OF CANCER, 2019, 120 (03) : 286 - 293
  • [13] Phase I trial with farnesyltransferase inhibitor R115777 in patients (pts) with advanced solid tumors
    Punt, CJA
    Peters, M
    van Maanen, L
    van de Walle, B
    Bol, C
    Willems, L
    Horak, I
    Palmer, P
    Wagener, DJT
    EUROPEAN JOURNAL OF CANCER, 1999, 35 : S291 - S291
  • [14] A phase I pharmacokinetic, pharmacogenomic trial of weekly amonafide in patients (pts) with solid tumors.
    Kuhn, JG
    Jones, S
    Hein, D
    Willcutt, N
    Greco, FA
    Raefsky, E
    Thompson, D
    Meluch, A
    Brown, D
    Burris, H
    JOURNAL OF CLINICAL ONCOLOGY, 2004, 22 (14) : 132S - 132S
  • [15] A phase I trial of X-396, a novel ALK inhibitor, in patients with advanced solid tumors.
    Horn, Leora
    Infante, Jeffrey R.
    Blumenschein, George R.
    Wakelee, Heather A.
    Arkenau, Hendrik-Tobias
    Dukart, Gary
    Liang, Chris
    Harrow, Kimberly
    Gibbons, Jay
    Lovly, Christine Marie
    Pao, William
    JOURNAL OF CLINICAL ONCOLOGY, 2014, 32 (15)
  • [16] Phase I trial of the programmed death receptor 1 (PD-1) inhibitor, BI 754091, in patients (pts) with advanced solid tumors.
    Johnson, Melissa Lynne
    Patel, Manish R.
    Siu, Lillian L.
    Kozloff, Mark
    Aljumaily, Raid
    Vaishampayan, Ulka N.
    Elgadi, Mabrouk M.
    Ge, Miaomiao
    Duffy, Christine
    Graeser, Ralph
    Khedkar, Sheetal Vinay
    Jones, Suzanne Fields
    Burris, Howard A.
    JOURNAL OF CLINICAL ONCOLOGY, 2018, 36 (05)
  • [17] A phase I first-in-human study of PRI-724 in patients (pts) with advanced solid tumors.
    El-Khoueiry, Anthony B.
    Ning, Yan
    Yang, Dongyun
    Cole, Sarah
    Kahn, Michael
    Zoghbi, Marwan
    Berg, Jennifer
    Fujimori, Masamoto
    Inada, Tetsuhi
    Kouji, Hiroyuki
    Lenz, Heinz-Josef
    JOURNAL OF CLINICAL ONCOLOGY, 2013, 31 (15)
  • [18] Phase I trial of imexon (IMX) in patients (pts) with advanced solid tumors
    Dragovich, T
    Mendelson, D
    Gordon, M
    Long, K
    Downhour, M
    Dorr, R
    Hersh, E
    JOURNAL OF CLINICAL ONCOLOGY, 2005, 23 (16) : 229S - 229S
  • [19] A phase I trial of the combination of erlotinib and tipifarnib in patients with advanced solid tumors.
    Ma, CX
    Croghan, G
    Reid, J
    Hanson, L
    Mandrekar, S
    Marks, R
    Adjei, A
    Furth, A
    JOURNAL OF CLINICAL ONCOLOGY, 2005, 23 (16) : 192S - 192S
  • [20] Phase I trial of cabazitaxel plus cisplatin in patients with advanced solid tumors.
    Lockhart, Albert C.
    Sundaram, Shankar
    Sarantopoulos, John
    Mita, Monica M.
    Lane, Alex R.
    Moseley, Jennifer L.
    Dedieu, Jean-Francois
    Stash, Diane
    Zhi, Xin
    Mazuir, Florent
    Mita, Alain C.
    JOURNAL OF CLINICAL ONCOLOGY, 2012, 30 (05)
12345