Rapid typing of Borrelia burgdorferi sensu lato species in specimens from patients with different manifestations of Lyme borreliosis

被引:43
|
作者
Lünemann, JD
Zarmas, S
Priem, S
Franz, J
Zschenderlein, R
Aberer, E
Klein, R
Schouls, L
Burmester, GR
Krause, A [3 ]
机构
[1] Natl Inst Publ Hlth & Environm, NL-3720 BA Bilthoven, Netherlands
[2] Graz Univ, Dept Dermatol, Graz, Austria
[3] Charite Univ Hosp, Dept Med Rheumatol & Clin Immunol, D-10098 Berlin, Germany
[4] Charite Univ Hosp, Dept Neurol, D-10098 Berlin, Germany
关键词
D O I
10.1128/JCM.39.3.1130-1133.2001
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
To further investigate the pathogenic potential of different Borrelia burgdorferi genospecies, specimens from 27 patients with different manifestations of Lyme borreliosis were analyzed by PCR and reverse line blotting (RLB). In samples from Lyme arthritis patients, B. burgdorferi. sensu stricto was predominantly identified, while in patients with neuroborreliosis or acrodermatitis, Borrelia garinii and Borrelia afzelii, respectively, were exclusively detected. The results demonstrate that PCR-RLB is a valuable tool for epidemiological and pathogenetic studies of Lyme borreliosis.
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收藏
页码:1130 / 1133
页数:4
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