S100A4 expression and prognosis of gastric cancer: a meta-analysis

被引：6
|
作者：
Wang, Y. [1 ]
Zhou, L. -B. [1 ]
Li, X. -H. [2 ]
机构：
[1] Anhui Med Univ, Affiliated Hosp 2, Dept Gen Surg, Hefei, Peoples R China
[2] Shanghai Eighth Peoples Hosp, Dept Digest Med, Shanghai, Peoples R China
来源：
GENETICS AND MOLECULAR RESEARCH | 2014年 / 13卷 / 04期
关键词：
S100A4; Prognosis; Gastric cancer; Meta-analysis; FAMILY;
D O I：
10.4238/2014.December.12.1
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The prognostic role of S100A4 in gastric cancer is still under debate. The present meta-analysis aimed to evaluate the relationship between S10A4 levels and the prognosis of gastric cancer. We performed a meta-analysis of published studies assessing the relationship between S100A4 and gastric cancer prognosis. We used the Revman 5.0 software to perform literature retrieval, article selection, data collection, and statistical analysis. A fixed-effect model was used to pool the hazard ratio (HR) and 95% confidence intervals (95%CI). A total of 7 eligible studies that included 1257 gastric cancer patients were analyzed. We did not find a prognostic value for S100A4 in gastric cancer (HR = 1.48, 95% CI = 0.77 to 2.82, P = 0.24). In conclusion, the present study indicated that S100A4 expression level is not a prognostic factor for gastric cancer.
引用
收藏
页码：10398 / 10403
页数：6
相关论文
共 50 条
  • [31] Prognostic significance of S100A4 mRNA and protein expression in colorectal cancer
    Kang, Yoon-Goo
    Jung, Chan-Kwon
    Lee, Ahwon
    Kang, Won-Kyung
    Oh, Seung-Taek
    Kang, Chang-Suk
    JOURNAL OF SURGICAL ONCOLOGY, 2012, 105 (02) : 119 - 124
  • [32] S100A4 expression is associated with poor prognosis in patients with resectable gastrointestinal stromal tumor
    Shen, Wenlong
    Tan, Xiaojie
    Hao, Fengyun
    LIBYAN JOURNAL OF MEDICINE, 2019, 14 (01)
  • [33] Expression of S100A4 in Renal Epithelial Neoplasms
    Wang, Li J.
    Matoso, Andres
    Sciandra, Katherine T.
    Yakirevich, Evgeny
    Sabo, Edmond
    Zhang, Ying
    Meitner, Patricia A.
    Tavares, Rosemarie
    Noble, Lelia
    Pareek, Gyan
    DeLellis, Ronald A.
    Resnick, Murray B.
    APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY, 2012, 20 (01) : 71 - 76
  • [34] Expression of CXCR4 and breast cancer prognosis: a systematic review and meta-analysis
    Zhigang Zhang
    Chao Ni
    Wuzhen Chen
    Ping Wu
    Zhen Wang
    Junhua Yin
    Jian Huang
    Fuming Qiu
    BMC Cancer, 14
  • [35] Chemokine receptor CXCR4 expression and lung cancer prognosis: a meta-analysis
    Liang, Jin-Xiao
    Gao, Wei
    Liang, Yong
    Zhou, Xin-Ming
    INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, 2015, 8 (04): : 5163 - 5174
  • [36] Higher expression of SALL4 predicts poor cancer prognosis: A meta-analysis
    Shen, Hongyu
    Li, Liangpeng
    Wang, Dandan
    Yang, Sujin
    Chen, Xiu
    Zhou, Siying
    Zhong, Shanliang
    Zhao, Jianhua
    Tang, Jinhai
    CANCER BIOMARKERS, 2017, 19 (04) : 365 - 373
  • [37] Expression of CXCR4 and breast cancer prognosis: a systematic review and meta-analysis
    Zhang, Zhigang
    Ni, Chao
    Chen, Wuzhen
    Wu, Ping
    Wang, Zhen
    Yin, Junhua
    Huang, Jian
    Qiu, Fuming
    BMC CANCER, 2014, 14
  • [38] Clinicopathologic significance of S100A4 expression in osteosarcoma
    Cao, C. -M.
    Yang, F. -X.
    Wang, P. -L.
    Yang, Q. -X.
    Sun, X. -R.
    EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, 2014, 18 (06) : 833 - 839
  • [39] FAM107B is regulated by S100A4 and mediates the effect of S100A4 on the proliferation and migration of MGC803 gastric cancer cells
    Guo, Junfu
    Bian, Yue
    Wang, Yu
    Chen, Lisha
    Yu, Aiwen
    Sun, Xiuju
    CELL BIOLOGY INTERNATIONAL, 2017, 41 (10) : 1103 - 1109
  • [40] EFFECT OF GARLIC IN GASTRIC CANCER PROGNOSIS: A SYSTEMATIC REVIEW AND META-ANALYSIS
    Alizadeh-Navaei, R.
    Shamshirian, A.
    Hedayatizadeh-Omran, A.
    Ghadimi, R.
    Janbabai, G.
    WORLD CANCER RESEARCH JOURNAL, 2018, 5 (04)
12345