Morphogenesis: Shaping Tissues through Extracellular Force Gradients

被引：4
|
作者：
Jayadev, Ranjay [1 ]
Sherwood, David R. [1 ]
机构：
[1] Duke Univ, Dept Biol, Regenerat Next, Durham, NC 27708 USA
来源：
CURRENT BIOLOGY | 2017年 / 27卷 / 17期
关键词：
BASEMENT-MEMBRANE; ORGAN; ARCHITECTURE; DROSOPHILA; MOVEMENT; PROTEASE; COLLAGEN; ROLES; IV;
D O I：
10.1016/j.cub.2017.07.040
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Organ sculpting requires directed physical force generation. Force imbalances are primarily thought to arise from within cells. A new study, however, demonstrates that an extracellular-matrix-based stiffness gradient in the Drosophila egg chamber instructs tissue elongation.
引用
收藏
页码：R850 / R852
页数：4
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