Comment: How do triptans work in migraine?

被引：1
|
作者：
Goadsby, Peter J. [1 ]
机构：
[1] Kings Coll London, NIHR Wellcome Trust Clin Res Facil, London WC2R 2LS, England
来源：
NEUROLOGY | 2015年 / 84卷 / 21期
关键词：
D O I：
10.1212/WNL.0000000000001623
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Triptans, serotonin 5-HT1B/1D receptor agonists, represent a milestone in migraine therapeutics: they are effective acute attack therapies with a clear pharmacology and no substantial nonheadache indications.(1) Their mechanism of action has never been entirely defined despite widespread use and the potential utility for medicine development in understanding the effect.
引用
收藏
页码：2129 / 2131
页数：3
相关论文
共 50 条
  • [31] Treatment of Perimenstrual Migraine with Triptans: an Update
    Barbara Casolla
    Luana Lionetto
    Serena Candela
    Lidia D’Alonzo
    Andrea Negro
    Maurizio Simmaco
    Paolo Martelletti
    [J]. Current Pain and Headache Reports, 2012, 16 : 445 - 451
  • [32] Acute management of migraine: triptans and beyond
    Diener, HC
    Limmroth, V
    [J]. CURRENT OPINION IN NEUROLOGY, 1999, 12 (03) : 261 - 267
  • [33] The economic burden of migraine: The role of the triptans
    不详
    [J]. AMERICAN JOURNAL OF MANAGED CARE, 1998, 4 (10): : S630 - S632
  • [34] New "triptans" and other drugs for migraine
    不详
    [J]. MEDICAL LETTER ON DRUGS AND THERAPEUTICS, 1998, 40 (1037): : 97 - 100
  • [35] The Use of Triptans in the Management of Menstrual Migraine
    Lisa K. Mannix
    Julia A. Files
    [J]. CNS Drugs, 2005, 19 : 951 - 972
  • [36] The Efficacy of Triptans in Childhood and Adolescence Migraine
    Stefan Evers
    [J]. Current Pain and Headache Reports, 2013, 17
  • [37] Formulation Approaches of Triptans for Management of Migraine
    Kassem, Abeer Ahmed
    [J]. CURRENT DRUG DELIVERY, 2016, 13 (06) : 882 - 898
  • [38] The safety of triptans in the treatment of patients with migraine
    Jamieson, DG
    [J]. AMERICAN JOURNAL OF MEDICINE, 2002, 112 (02): : 135 - 140
  • [39] Are the triptans for migraine therapy worth the cost?
    Becker, WJ
    [J]. CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES, 2000, 27 (02) : 111 - 115
  • [40] The Efficacy of Triptans in Childhood and Adolescence Migraine
    Evers, Stefan
    [J]. CURRENT PAIN AND HEADACHE REPORTS, 2013, 17 (07)
12345