Steps forward for cancer precision medicine

被引：29

作者：

Salgado, Roberto ^{[1
,2
,3
]}

Moore, Helen ^{[4
,5
,6
,7
]}

Martens, John W. M. ^{[8
,9
]}

Lively, Tracy ^{[4
,5
,6
,7
]}

Malik, Shakun ^{[4
,5
,6
,7
]}

McDermott, Ultan ^{[10
]}

Michiels, Stefan ^{[11
]}

Moscow, Jeffrey A. ^{[4
,5
,6
,7
]}

Tejpar, Sabine ^{[12
]}

McKee, Tawnya ^{[4
,5
,6
,7
]}

Lacombe, Denis ^{[13
]}

机构：

[1] Gasthuiszusters Antwerpen, Dept Pathol, Antwerp, Belgium

[2] Jules Bordet Inst, Breast Canc Translat Res Lab, Brussels, Belgium

[3] Univ Melbourne, Peter MacCallum Canc Ctr, Melbourne, Vic, Australia

[4] NCI, Biorepositories & Biospecimen Res Branch, NIH, Bethesda, MD 20892 USA

[5] NCI, DCTD, NIH, Bethesda, MD 20892 USA

[6] NCI, Canc Therapy Evaluat Program, NIH, Bethesda, MD 20892 USA

[7] NCI, Invest Drug Branch, NIH, Bethesda, MD 20892 USA

[8] Erasmus Univ, Med Ctr, Erasmus MC Canc Inst, Rotterdam, Netherlands

[9] Erasmus Univ, Med Ctr, Canc Genom Netherlands, Rotterdam, Netherlands

[10] Wellcome Trust Sanger Inst, Cambridge, England

[11] Univ Paris Saclay, Univ Paris Sud, INSERM, Villejuif, France

[12] Univ Hosp Gasthuisberg, Leuven, Belgium

[13] EORTC Headquarters, B-1200 Brussels, Belgium

来源：

NATURE REVIEWS DRUG DISCOVERY | 2018年 / 17卷 / 01期

关键词：

DIAGNOSTICS;

D O I：

10.1038/nrd.2017.218

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The availability of targeted anticancer drugs and the relative affordability of genomic analyses has led to a growing expectation among patients with cancer that they can receive personalized treatment based on the genomic signature of their tumour. Here, we discuss some of the challenges and steps needed to bring such approaches into routine practice.

引用

页码：1 / 2

页数：2

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