Low effectiveness of seasonal influenza vaccine in preventing laboratory-confirmed influenza in primary care in the United Kingdom: 2014/15 mid-season results

被引：1
|
作者：
Pebody, R. G. [1 ]
Warburton, F. [1 ]
Ellis, J. [2 ]
Andrews, N. [1 ]
Thompson, C. [2 ]
von Wissmann, B. [3 ]
Green, H. K. [1 ]
Cottrell, S. [4 ]
Johnston, J. [5 ]
de Lusignan, S.
Moore, C. [6 ]
Gunson, R. [7 ]
Robertson, C. [9 ]
McMenamin, J. [3 ,8 ]
Zambon, M. [2 ]
机构：
[1] Publ Hlth England Ctr Infect Dis Surveillance & C, London, England
[2] Microbiol Serv, Publ Hlth England Operat Directorate, London, England
[3] Hlth Protect Scotland, Glasgow, Lanark, Scotland
[4] Publ Hlth Wales, Cardiff, S Glam, Wales
[5] Publ Hlth Agcy Northern Ireland, Belfast, Antrim, North Ireland
[6] Publ Hlth Wales Mol Diagnost Unit, Cardiff, S Glam, Wales
[7] West Scotland Specialist Virol Ctr, Glasgow, Lanark, Scotland
[8] Univ Strathclyde, Glasgow, Lanark, Scotland
[9] Int Prevent Res Inst, Lyon, France
来源：
EUROSURVEILLANCE | 2015年 / 20卷 / 05期
关键词：
PCR;
D O I：
暂无
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
In 2014/15 the United Kingdom experienced circulation of influenza A(H3N2) with impact in the elderly. Mid-season vaccine effectiveness (VE) shows an adjusted VE of 3.4% (95% CI: -44.8 to 35.5) against primary care consultation with laboratory-confirmed influenza and -2.3% (95% CI: -56.2 to 33.0) for A(H3N2). The low VE reflects mismatch between circulating viruses and the 2014/15 northern hemisphere A(H3N2) vaccine strain. Early use of antivirals for prophylaxis and treatment of vulnerable populations remains important.
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页码：6 / 12
页数：7
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