Low effectiveness of seasonal influenza vaccine in preventing laboratory-confirmed influenza in primary care in the United Kingdom: 2014/15 mid-season results

被引：1

作者：

Pebody, R. G. ^{[1
]}

Warburton, F. ^{[1
]}

Ellis, J. ^{[2
]}

Andrews, N. ^{[1
]}

Thompson, C. ^{[2
]}

von Wissmann, B. ^{[3
]}

Green, H. K. ^{[1
]}

Cottrell, S. ^{[4
]}

Johnston, J. ^{[5
]}

de Lusignan, S.

Moore, C. ^{[6
]}

Gunson, R. ^{[7
]}

Robertson, C. ^{[9
]}

McMenamin, J. ^{[3
,8
]}

Zambon, M. ^{[2
]}

机构：

[1] Publ Hlth England Ctr Infect Dis Surveillance & C, London, England

[2] Microbiol Serv, Publ Hlth England Operat Directorate, London, England

[3] Hlth Protect Scotland, Glasgow, Lanark, Scotland

[4] Publ Hlth Wales, Cardiff, S Glam, Wales

[5] Publ Hlth Agcy Northern Ireland, Belfast, Antrim, North Ireland

[6] Publ Hlth Wales Mol Diagnost Unit, Cardiff, S Glam, Wales

[7] West Scotland Specialist Virol Ctr, Glasgow, Lanark, Scotland

[8] Univ Strathclyde, Glasgow, Lanark, Scotland

[9] Int Prevent Res Inst, Lyon, France

来源：

EUROSURVEILLANCE | 2015年 / 20卷 / 05期

关键词：

PCR;

D O I：

暂无

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

In 2014/15 the United Kingdom experienced circulation of influenza A(H3N2) with impact in the elderly. Mid-season vaccine effectiveness (VE) shows an adjusted VE of 3.4% (95% CI: -44.8 to 35.5) against primary care consultation with laboratory-confirmed influenza and -2.3% (95% CI: -56.2 to 33.0) for A(H3N2). The low VE reflects mismatch between circulating viruses and the 2014/15 northern hemisphere A(H3N2) vaccine strain. Early use of antivirals for prophylaxis and treatment of vulnerable populations remains important.

引用

页码：6 / 12

页数：7

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