Highly enantioselective synthesis of chiral allylic alcohols by asymmetric addition of novel mixed reagents of trialkenylbismuthines/dialkylzincs to aldehydes

被引：18
|
作者：
Sato, Itaru [1 ]
Asakura, Noriaki [1 ]
Iwashita, Taizo [1 ]
机构：
[1] Kwansei Gakuin Univ, Sch Sci & Technol, Dept Chem, Sanda, Hyogo 6691337, Japan
来源：
TETRAHEDRON-ASYMMETRY | 2007年 / 18卷 / 22期
关键词：
D O I：
10.1016/j.tetasy.2007.10.031
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
A novel mixture of reagents of trialkenylbismuthines/dialkylzines was developed and applied toward the synthesis of chiral allylic alcohols. The chiral beta-amino alcohols catalyzed addition of the mixed reagents of trialkenylbismuthines/dialkylzincs to aldehydes gave enantiomerically enriched allylic alcohols with up to 97% ee. (c) 2007 Elsevier Ltd. All rights reserved.
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页码：2638 / 2642
页数：5
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