Objectives To measure the dose discrepancy in prescribing simple paediatric analgesia, in the emergency department, by comparing age and actual weight-based dosing. To establish the accuracy of the weight-estimation formula for children [weight kg = 2 (age years + 4)]. Methods A prospective survey conducted in the emergency departments of a UK teaching hospital and district general hospital. Two hundred and forty-seven children were prescribed simple analgesia in the form of paracetamol and ibuprofen or both. The dose prescribed was based on age. All children were weighed and a maximum dose based on the child's weight was calculated. The individual child's weight was also compared with the weight calculated using the estimation formula. Results A total of 247 patients were included. Two hundred and thirty-three patients were prescribed paracetamol. Fifteen patients were prescribed ibuprofen. The paracetamol group was administered a mean dose that was 67% (P < 0.001) of the optimal dose that was based on weight. lbuprofen dosage was 51% (P < 0.001) of optimal dose. The weight-estimation formula underestimated weight by 16% (P < 0.001). Conclusions Prescribing analgesia by age often results in significant underdlosing in the paediatric population. Predicting a child's weight using the calculation may result in underdosing.
机构:
NYU, Sch Med, Dept Emergency Med, New York, NY 10003 USA
NYU, Sch Med, Dept Populat Hlth, New York, NY 10003 USANYU, Sch Med, Dept Emergency Med, New York, NY 10003 USA
Doran, Kelly M.
Raja, Ali S.
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机构:
Massachusetts Gen Hosp, Dept Emergency Med, Boston, MA 02114 USA
Harvard Med Sch, Boston, MA USANYU, Sch Med, Dept Emergency Med, New York, NY 10003 USA
Raja, Ali S.
Samuels, Elizabeth A.
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机构:
Yale Sch Med, Natl Clinician Scholars Program, New Haven, CT USA
Yale Sch Med, Dept Emergency Med, New Haven, CT USANYU, Sch Med, Dept Emergency Med, New York, NY 10003 USA