Comparison of survival of adolescents and young adults with hematologic malignancies in Osaka, Japan

被引：6

作者：

Nakata-Yamada, Kayo ^{[1
]}

Inoue, Masami ^{[2
]}

Ioka, Akiko ^{[1
]}

Ito, Yuri ^{[1
]}

Tabuchi, Takahiro ^{[1
]}

Miyashiro, Isao ^{[1
]}

Masaie, Hiroaki ^{[3
]}

Ishikawa, Jun ^{[3
]}

Hino, Masayuki ^{[4
]}

Tsukuma, Hideaki ^{[1
]}

机构：

[1] Osaka Med Ctr Canc & Cardiovasc Dis, Ctr Canc Control & Stat, Osaka 5378511, Japan

[2] Osaka Med Ctr & Res Inst Maternal & Child Hlth, Dept Hematol Oncol, Osaka, Japan

[3] Osaka Med Ctr Canc & Cardiovasc Dis, Dept Hematol Oncol, Osaka 5378511, Japan

[4] Osaka City Univ, Dept Hematol, Grad Sch Med, Osaka 558, Japan

来源：

LEUKEMIA & LYMPHOMA | 2016年 / 57卷 / 06期

关键词：

Adolescents and young adults; hematological malignancies; leukemia; lymphoma; survival; ACUTE LYMPHOBLASTIC-LEUKEMIA; ACUTE MYELOID-LEUKEMIA; CANCER; OUTCOMES; AGE; CHILDHOOD; ONCOLOGY; CHILDREN; TRENDS; PARTICIPATION;

D O I：

10.3109/10428194.2015.1083562

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The survival gap between adolescents and young adults (AYAs) with hematological malignancies persists in many countries. To determine to what extent it does in Japan, we investigated survival and treatment regimens in 211 Japanese AYAs (15-29 years) in the Osaka Cancer Registry diagnosed during 2001-2005 with hematological malignancies, and compared adolescents (15-19 years) with young adults (20-29 years). AYAs with acute lymphoblastic leukemia (ALL) had a poor 5-year survival (44%), particularly young adults (29% vs. 64% in adolescents, p=0.01). Additional investigation for patients with ALL revealed that only 19% of young adults were treated with pediatric treatment regimens compared with 45% of adolescents (p=0.05). Our data indicate that we need to focus on young adults with ALL and to consider establishing appropriate cancer care system and guidelines for them in Japan.

引用

页码：1342 / 1348

页数：7

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