Human dendritic cell subsets: An updated view of their ontogeny and functional specialization

被引：30
|
作者：
Segura, Elodie [1 ]
机构：
[1] PSL Res Univ, Inst Curie, Paris, France
来源：
EUROPEAN JOURNAL OF IMMUNOLOGY | 2022年 / 52卷 / 11期
关键词：
Human; dendritic cell; subsets; ANTIGEN CROSS-PRESENTATION; T-CELLS; DISTINCT SUBSETS; INFECTED CELLS; HUMAN CD1C(+); FACTOR E2-2; DIFFERENTIATION; MONOCYTES; VIRUS; HETEROGENEITY;
D O I：
10.1002/eji.202149632
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Human DCs have been divided into several subsets based on their phenotype and ontogeny. Recent high throughput single-cell methods have revealed additional heterogeneity within human DC subsets, and new subpopulations have been proposed. In this review, we provide an updated view of the human DC subsets and of their ontogeny supported by recent clinical studies . We also summarize their main characteristics including their functional specialization.
引用
收藏
页码：1759 / 1767
页数：9
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