Small fields:: Nonequilibrium radiation dosimetry

被引:520
|
作者
Das, Indra J. [1 ]
Ding, George X. [2 ]
Ahnesjo, Anders [3 ,4 ]
机构
[1] Univ Penn, Dept Radiat Oncol, Philadelphia, PA 19104 USA
[2] Vanderbilt Univ, Sch Med, Dept Radiat Oncol, Nashville, TN 37232 USA
[3] Uppsala Univ, Sect Oncol, Dept Oncol Radiol & Clin Immunol, S-75185 Uppsala, Sweden
[4] Uppsala & Nucletron AB, S-75147 Uppsala, Sweden
关键词
small field dosimetry; nonequilibrium conditions; Monte Carlo;
D O I
10.1118/1.2815356
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Advances in radiation treatment with beamlet-based intensity modulation, image-guided radiation therapy, and stereotactic radiosurgery (including specialized equipments like CyberKnife, Gamma Knife, tomotherapy, and high-resolution multileaf collimating systems) have resulted in the use of reduced treatment fields to a subcentimeter scale. Compared to the traditional radiotherapy with fields >= 4 x 4 cm(2), this can result in significant uncertainty in the accuracy of clinical dosimetry. The dosimetry of small fields is challenging due to nonequilibrium conditions created as a consequence of the secondary electron track lengths and the source size projected through the collimating system that are comparable to the treatment field size. It is further complicated by the prolonged electron tracks in the presence of low-density inhomogeneities. Also, radiation detectors introduced into such fields usually perturb the level of disequilibrium. Hence, the dosimetric accuracy previously achieved for standard radiotherapy applications is at risk for both absolute and relative dose determination. This article summarizes the present knowledge and gives an insight into the future procedures to handle the nonequilibrium radiation dosimetry problems. It is anticipated that new miniature detectors with controlled perturbations and corrections will be available to meet the demand for accurate measurements. It is also expected that the Monte Carlo techniques will increasingly be used in assessing the accuracy, verification, and calculation of dose, and will aid perturbation calculations of detectors used in small and highly conformal radiation beams. (c) 2008 American Association of Physicists in Medicine.
引用
收藏
页码:206 / 215
页数:10
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