Impact of IgG Fab-glycosylation on transplacental transfer of antibodies and their binding to the neonatal Fc-receptor (FcRn)

被引:0
|
作者
Volkov, Mikhail [1 ]
van Schie, Karin A. J. [1 ]
Bondt, Albert [2 ]
Kissel, Theresa [1 ]
Brinkhaus, Max [3 ]
Bentlage, Arthur [3 ]
Koeleman, Carolien [1 ]
de Taeye, Stephen [3 ]
Dolhain, Radboud J. E. M. [4 ]
Wuhrer, Manfred [5 ]
Huizinga, Tom W. J. [1 ]
Toes, Rene E. M. [1 ]
Vidarsson, Gestur [3 ]
van der Woude, Diane [1 ]
机构
[1] Leiden Univ, Dept Rheumatol, Med Ctr, Leiden, Netherlands
[2] Univ Utrecht, Biomol Mass Spectrometry & Prote, Utrecht, Netherlands
[3] Sanquin Res, Immunoglobulin Res, Amsterdam, Netherlands
[4] Erasmus MC, Dept Rheumatol, Rotterdam, Netherlands
[5] Leiden Univ, Ctr Prote & Metabol, Med Ctr, Leiden, Netherlands
关键词
Adaptive immunity; antibody; B lymphocytes; biology of the immune system;
D O I
暂无
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
P-0023
引用
收藏
页码:134 / 134
页数:1
相关论文
共 50 条
  • [21] Characterization and screening of IgG binding to the neonatal Fc receptor
    Neuber, Tobias
    Frese, Katrin
    Jaehrling, Jan
    Jaeger, Sebastian
    Daubert, Daniela
    Felderer, Karin
    Linnemann, Mechthild
    Hoehne, Anne
    Kaden, Stefan
    Koelln, Johanna
    Tiller, Thomas
    Brocks, Bodo
    Ostendorp, Ralf
    Pabst, Stefan
    MABS, 2014, 6 (04) : 928 - 942
  • [22] Neonatal Fc receptor for IgG (FcRn) expressed in the gastric epithelium regulates bacterial infection in mice
    Ben Suleiman, Y.
    Yoshida, M.
    Nishiumi, S.
    Tanaka, H.
    Mimura, T.
    Nobutani, K.
    Yamamoto, K.
    Takenaka, M.
    Aoganghua, A.
    Miki, I.
    Ota, H.
    Takahashi, S.
    Matsui, H.
    Nakamura, M.
    Blumberg, R. S.
    Azuma, T.
    MUCOSAL IMMUNOLOGY, 2012, 5 (01) : 87 - 98
  • [23] The neonatal Fc receptor (FcRn) binds independently to both sites of the IgG homodimer with identical affinity
    Abdiche, Yasmina Noubia
    Yeung, Yik Andy
    Chaparro-Riggers, Javier
    Barman, Ishita
    Strop, Pavel
    Chin, Sherman Michael
    Pham, Amber
    Bolton, Gary
    McDonough, Dan
    Lindquist, Kevin
    Pons, Jaume
    Rajpal, Arvind
    MABS, 2015, 7 (02) : 331 - 343
  • [24] Reducing IgG accumulation via neonatal Fc receptor (FcRn) blockade relieves neuropathic pain
    Fiore, Nathan T.
    Willcox, Kendal F.
    Dayani, Dorsa
    Zuberi, Younus A.
    Heijnen, Cobi J.
    Grace, Peter M.
    BRAIN BEHAVIOR AND IMMUNITY, 2025, 125 : 371 - 387
  • [25] Impact of methionine oxidation on the binding of human IgG1 to FcRn and Fcγ receptors
    Bertolotti-Ciarlet, Andrea
    Wang, Weirong
    Lownes, Rebecca
    Pristatsky, Pavlo
    Fang, Yulin
    McKelvey, Troy
    Li, Yingzhe
    Li, Yunsong
    Drummond, James
    Prueksaritanont, Thomayant
    Vlasak, Josef
    MOLECULAR IMMUNOLOGY, 2009, 46 (8-9) : 1878 - 1882
  • [26] Identification of critical IgG binding epitopes on the neonatal Fc receptor
    Vaughn, DE
    Milburn, CM
    Penny, DM
    Martin, WL
    Johnson, JL
    Bjorkman, PJ
    JOURNAL OF MOLECULAR BIOLOGY, 1997, 274 (04) : 597 - 607
  • [27] SITE OF BINDING OF MOUSE IGG2B TO THE FC-RECEPTOR ON MOUSE MACROPHAGES
    DIAMOND, B
    BIRSHTEIN, BK
    SCHARFF, MD
    JOURNAL OF EXPERIMENTAL MEDICINE, 1979, 150 (03): : 721 - 726
  • [28] Neonatal Fc receptor impacts the subcutaneous bioavailability of monoclonal IGG antibodies
    Garg, Amit
    Lowe, Philip J.
    Balthasar, Joseph P.
    JOURNAL OF CLINICAL PHARMACOLOGY, 2008, 48 (09): : 1131 - 1131
  • [29] Field flow fractionation for assessing FcRn and Fcγ receptor binding to monoclonal antibodies in solution
    Chou, Robert Y-T
    Pollastrini, Joey
    Dillon, Thomas M.
    Bondarenko, Pavel
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2011, 241
  • [30] TRANSPLACENTAL TRANSFER OF MATERNAL MALARIA-SPECIFIC IGG3 IS ALTERED BY A POLYMORPHISM IN THE BINDING DOMAIN TO FCRN
    Dechavanne, Celia
    Alvarado, Fernanda
    Dambrun, Magalie
    Dugoujeon, Jean-Michel
    Guitard, Evelyne
    Malhorta, Indu
    Garcia, Andre
    Migot-Nabias, Florence
    King, Christopher L.
    AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 2017, 95 (05): : 506 - 506