Biosensor platforms for biomarker detection: plasmonic aptasensors for detection of Neuropeptide Y

被引：2
|
作者：
Chavez, Jorge L. [1 ]
Rieger, Kelsey [1 ]
Hagen, Joshua A. [1 ,2 ]
Kelley-Loughnane, Nancy [1 ]
机构：
[1] US Air Force, Res Lab, 711th Human Performance Wing, Wright Patterson AFB, OH 45433 USA
[2] West Virginia Univ, Dept Neurosci, Human Performance Innovat Ctr, Morgantown, WV 26506 USA
来源：
SMART BIOMEDICAL AND PHYSIOLOGICAL SENSOR TECHNOLOGY XV | 2019年 / 11020卷
关键词：
aptamer; gold nanoparticle; plasmonic; neuropeptide Y;
D O I：
10.1117/12.2520330
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
A Neuropeptide Y-binding aptamer (NPY-BA) and 15 nm gold nanoparticles (AuNPs) were used to create plasmonic aptasensors for the selective detection of Neuropeptide Y in a rapid colorimetric assay. In this report, we describe different parameters that can be varied to optimize the sensitivity and selectivity of these assay and demonstrate initial NPY detection in sweat.
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页数：7
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