Catalytic Behaviors in Modulating Enzymatic Activity through Different-sized Gold Nanoparticles

被引:0
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作者
Wu, Chung-Shu [1 ]
Wu, Chia-Tien [1 ]
Chen, Chieh [1 ]
Huang, Chung-Chih [1 ]
Yeh, Yu-Lin [1 ]
Yang, Yuh-Shyong [2 ]
Ko, Fu-Hsiang [1 ]
机构
[1] Natl Chiao Tung Univ, Inst Nanotechnol, Hsinchu 300, Taiwan
[2] Natl Chiao Tung Univ, Dept Biol Sci & Technol, Hsinchu 300, Taiwan
关键词
FIELD-EFFECT TRANSISTOR;
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中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
We have demonstrated that gold nanoparticles (AuNPs) can effectively associate with enzyme through spontaneous adsorption to afford supramolecular complexes, resulting in a significant increase of its enzymatic activity. In this work, we embarked on a study of the interactions between the different-sized AuNPs and the substrate through quantifying the kinetic parameters (K-cat and K-m). The diversity of size allows us to probe the role of catalytic behaviors in modulating enzymatic activity.
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页码:334 / +
页数:2
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