Lowered leptin slims immune response

被引：63
|
作者：
Flier, JS [1 ]
机构：
[1] Beth Israel Deaconess Med Ctr, Dept Med, Div Endocrinol, Boston, MA 02215 USA
来源：
NATURE MEDICINE | 1998年 / 4卷 / 10期
关键词：
D O I：
10.1038/2619
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The decrease in leptin induced by starvation causes immune suppression, further demonstrating that falling and rising leptin levels have major, and quite distinct, physiologic consequences.
引用
收藏
页码：1124 / 1125
页数：2
相关论文
共 50 条
  • [41] Lowered immune system reactivity as a feature of Alzheimer Disease patients with hypocomplementemia
    Venturini, L.
    Osera, C.
    Pascale, A.
    Amadio, M.
    Sardi, F.
    Mainardi, M.
    Govoni, S.
    Ricevuti, G.
    IMMUNOLOGY, 2010, 131 : 190 - 190
  • [42] The colonisation of saline waters is associated with lowered immune responses in aquatic beetles
    Botella-Cruz, Maria
    Pallares, Susana
    Velasco, Josefa
    Moody, A. John
    Billington, Richard
    Millan, Andres
    Bilton, David T.
    FRESHWATER BIOLOGY, 2022, 67 (12) : 2024 - 2034
  • [43] Leptin and leptin receptor gene polymorphisms and depression treatment response
    Tavast, Ida-Maria
    Solismaa, Anssi
    Lyytikainen, Leo-Pekka
    Mononen, Nina
    Moilanen, Eeva
    Hamalainen, Mari
    Lehtimaki, Terho
    Kampman, Olli
    ACTA NEUROPSYCHIATRICA, 2024,
  • [44] Detective leptin signaling improves regulatory T cell immune response and protects mice from atherosclerosis
    Taleb, Soraya
    Herbin, Olivier
    Ait-Oufella, Hafid
    Verreth, Wirn
    Gourdy, Pierre
    Barateau, Veromque
    Merval, Regine
    Esposito, Bruno
    Clement, Karine
    Holvoet, Paul
    Tedgui, Alain
    Mallat, Ziad
    CIRCULATION, 2007, 116 (16) : 145 - 145
  • [45] Leptin ameliorates burn-induced multiple organ damage and modulates postburn immune response in rats
    Çakir, B
    Çevik, H
    Contuk, G
    Ercan, F
    Eksioglu-Demiralp, E
    Yegen, BÇ
    REGULATORY PEPTIDES, 2005, 125 (1-3) : 135 - 144
  • [46] Leptin Receptor-Related Immune Response in Colorectal Tumors: The Role of Colonocytes and Interleukin-8
    Abolhassani, Mohammad
    Aloulou, Nijez
    Chaumette, Marie Therese
    Aparicio, Thomas
    Martin-Garcia, Nadine
    Mansour, Hicham
    Le Gouvello, Sabine
    Delchier, Jean Charles
    Sobhani, Iradj
    CANCER RESEARCH, 2008, 68 (22) : 9423 - 9432
  • [47] The acute leptin response to GH
    Lissett, CA
    Clayton, PE
    Shalet, SM
    JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2001, 86 (09): : 4412 - 4415
  • [48] The response of skeletal muscle to leptin
    Ceddia, RB
    William, WN
    Curi, R
    FRONTIERS IN BIOSCIENCE-LANDMARK, 2001, 6 : D90 - D97
  • [49] Leptin, obesity, and response to ketamine
    Rashidian, Houman
    Rosenblat, Joshua D.
    McIntyre, Roger S.
    Mansur, Rodrigo B.
    PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, 2020, 98
  • [50] The role of leptin in innate and adaptive immune responses
    Bernotiene, Eiva
    Palmer, Gaby
    Gabay, Cem
    ARTHRITIS RESEARCH & THERAPY, 2006, 8 (05)
12345