Synthesis and biological activity of N-acylated ornithine analogues of daptomycin

被引:44
|
作者
Hill, J [1 ]
Siedlecki, J [1 ]
Parr, I [1 ]
Morytko, M [1 ]
Yu, X [1 ]
Zhang, YZ [1 ]
Silverman, J [1 ]
Controneo, N [1 ]
Laganas, V [1 ]
Li, TC [1 ]
Lai, JJ [1 ]
Keith, D [1 ]
Shimer, G [1 ]
Finn, J [1 ]
机构
[1] Cubist Pharmaceut Inc, Lexington, MA 02421 USA
关键词
D O I
10.1016/j.bmcl.2003.07.019
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
N-Acylated ornithine analogues of daptomycin were synthesized and tested for their antibacterial efficacy. (C) 2003 Elsevier Ltd. All rights reserved.
引用
收藏
页码:4187 / 4191
页数:5
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