RESEARCH PROGRESS ON THE PHARMACOLOGICAL ACTION AND MECHANISM OF NEOHESPERIDIN DIHYDROCHALCONE

被引：0
|
作者：
Xia Hong [1 ]
Song Jian [2 ]
Ye Jianzhong [1 ]
Ding Wenwen [1 ]
机构：
[1] Jingchu Univ Technol, Med Coll, Jingmen, Peoples R China
[2] Jingzhou Vocat & Tech Coll, Jingzhou, Peoples R China
来源：
ACTA MEDICA MEDITERRANEA | 2022年 / 38卷 / 03期
关键词：
NHDC; flavonoids; anti-inflammatory immunity; antioxidant; ANTIOXIDANT PROPERTIES; SWEETENER; DEGRADATION; HESPERIDIN; INJURY;
D O I：
10.19193/0393-6384_2022_3_222
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Introduction: Neohesperidin dihydrochalcone (NHDC) is a derivative of chalcone, with good stability, safety and non-toxicity, and is widely used in food, aquaculture and pharmaceuticals. Materials and methods: According to the relevant literature, NHDC showed good antioxidant activity against carbon tetrachloride-induced oxidative damage in mouse liver and human hepatoma cell lines and good scavenging activity against the generated oxygen free radicals, suggesting that it may it has a therapeutic effect on inflammatory diseases. Results and conclusion: This article reviews the research progress of the pharmacological effects of NHDC, and provides a scientific basis for the in-depth research of NHDC and the further comprehensive development and utilization of plant resources.
引用
收藏
页码：1477 / 1480
页数：4
相关论文
共 50 条
  • [21] Effect of pH on neohesperidin dihydrochalcone thermostability in aqueous solutions
    Coiffard, C
    Coiffard, L
    Peigne, F
    De Roeck-Holtzhauer, Y
    ANALUSIS, 1998, 26 (03) : 150 - 153
  • [22] Improved water solubility of neohesperidin dihydrochalcone in sweetener blends
    Benavente-García, O
    Castillo, J
    Del Baño, MJ
    Lorente, J
    JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2001, 49 (01) : 189 - 191
  • [23] TASTE RESPONSES TO NEOHESPERIDIN DIHYDROCHALCONE IN RATS AND BABOON MONKEYS
    NAIM, M
    ROGATKA, H
    YAMAMOTO, T
    ZEHAVI, U
    PHYSIOLOGY & BEHAVIOR, 1982, 28 (06) : 979 - 986
  • [24] Neohesperidin Dihydrochalcone Improves Hyperglycemia and Insulin Resistance in Diabetic Zebrafish
    Tao, Fuying
    Wang, Pei
    Dai, Ziru
    Zhang, Chenxiao
    Li, Dongliang
    Fan, Heliang
    Qin, Mei
    Qi, Cen
    Hao, Junguang
    ACS FOOD SCIENCE & TECHNOLOGY, 2023, 3 (09): : 1548 - 1558
  • [25] Development of a HPLC-UV Method for the Separation and Quantification of Hesperidin, Neohesperidin, Neohesperidin Dihydrochalcone and Hesperetin
    Chen, Lin
    Zhu, Siming
    Wang, Chunqing
    Chen, Liang
    NATURAL PRODUCT RESEARCH, 2023, 37 (10) : 1714 - 1718
  • [26] Analysis of commercial neohesperidin dihydrochalcone by high performance liquid chromatography
    Castellar, MR
    Iborra, JL
    Canales, I
    JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES, 1997, 20 (13) : 2063 - 2073
  • [27] The binding site for neohesperidin dihydrochalcone at the human sweet taste receptor
    Winnig, Marcel
    Bufe, Bernd
    Kratochwil, Nicole A.
    Slack, Jay P.
    Meyerhof, Wolfgang
    BMC STRUCTURAL BIOLOGY, 2007, 7
  • [28] Selection of citrus varieties highly productive for the neohesperidin dihydrochalcone precursor
    DelRio, JA
    Fuster, MD
    Sabater, F
    Porras, I
    GarciaLidon, A
    Ortuno, A
    FOOD CHEMISTRY, 1997, 59 (03) : 433 - 437
  • [29] Research Progress on the Toxicity and Mechanism of Action of Patulin
    Li Y.
    Shan S.
    Wu D.
    Hu S.
    Xu Z.
    Zhu R.
    Shipin Kexue/Food Science, 2023, 44 (11): : 309 - 316
  • [30] Research progress of specific bioactivity and pharmacological action of Ginkgo seed
    ZHAO, Peini
    HE, Fatao
    SONG, Ye
    WU, Maoyu
    GE, Bangguo
    LIU, Guangpeng
    Huagong Jinzhan/Chemical Industry and Engineering Progress, 2017, 36 (S1): : 366 - 371
12345