Vertebral Myeloma Mimicking Prostatic Carcinoma Metastasis in 68Ga-PSMA PET/CT

被引：21
|
作者：
Merrild, Esben Hoej [1 ]
Baerentzen, Steen [2 ]
Bouchelouche, Kirsten [3 ,4 ]
Buus, Simon [1 ]
机构：
[1] Aarhus Univ Hosp, Dept Oncol, Palle Juul Jensens Blvd 99, DK-8200 Aarhus N, Denmark
[2] Aarhus Univ Hosp, Dept Pathol, Aarhus, Denmark
[3] Aarhus Univ Hosp, Dept Nucl Med, Aarhus, Denmark
[4] Aarhus Univ Hosp, PET Ctr, Aarhus, Denmark
来源：
CLINICAL NUCLEAR MEDICINE | 2017年 / 42卷 / 10期
关键词：
multiple myeloma; prostate cancer; PSMA PET/CT;
D O I：
10.1097/RLU.0000000000001773
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
Ga-68-PSMA PET/CT was performed in a 75-year-old man with newly diagnosed prostate cancer because of an equivocal lesion in the spine both on Tc-99m-bone-SPECT/CT and MRI. Because of increased PSMA activity on PET/CT, the bone lesion was interpreted as metastasis from prostate cancer. Later, the patient was diagnosed as having monoclonal gammopathy of unknown significance. A biopsy was performed, and histological examination revealed multiple myeloma with PSMA expression in the neovessels but no metastatic prostate cancer cells. The patient was downstaged, and the treatment was changed accordingly. This case illustrates the importance of biopsies from PSMA PET-positive lesions.
引用
收藏
页码：790 / 792
页数：3
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