Multicentric Castleman's disease associated with inherited epidermolysis bullosa

被引：3
|
作者：
Kawakami, Y
Nishibu, A
Kikuchi, S
Ohtsuka, M
Nakamura, K
Nozawa, Y
Abe, M
Iwatsuki, K
Kaneko, F
机构：
[1] Fukushima Med Univ, Sch Med, Dept Dermatol, Fukushima 9601295, Japan
[2] Fukushima Med Univ, Sch Med, Dept Pathol 1, Fukushima 9601295, Japan
[3] Okayama Univ, Grad Sch Med & Dent, Dept Dermatol, Okayama 7008530, Japan
来源：
JOURNAL OF DERMATOLOGY | 2003年 / 30卷 / 09期
关键词：
interleukin-6; hypergammaglobulinemia; dystrophic epidermolysis bullosa;
D O I：
10.1111/j.1346-8138.2003.tb00459.x
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Multicentric Castleman's disease (MCD) is a rare disorder characterized by fever, polyclonal hypergammaglobulinemia, and generalized lymphadenopathy. It has three histological characteristics: a recognizable architecture, germinal center abnormalities, and plasmacytosis. Inherited epidermolysis bullosa (EB) is also a rare disorder caused by a genetic defect. We report a 43-year-old patient with dystrophic EB, non-Hallopeau-Siemens recessive type or dominant type, displaying clinicopathologic features of MCD. In addition, his serum interleukin-6, which is thought to be responsible for the clinical symptoms in MCD, was elevated.
引用
收藏
页码：689 / 693
页数：5
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