Human Cytochrome P450 2E1 metabolizes acrylamide to glycidamide

被引:0
|
作者
Settels, Eva [1 ]
Bernauer, Ulrike [1 ]
Palavinskas, Richard [1 ]
Klaffke, Horst Stefan [1 ]
Gundert-Remy, Ursula [1 ]
Appel, Klaus Erich [1 ]
机构
[1] Fed Inst Risk Assessment, Berlin, Germany
关键词
D O I
10.1016/j.toxlet.2007.05.291
中图分类号
R99 [毒物学(毒理学)];
学科分类号
100405 ;
摘要
引用
收藏
页码:S108 / S109
页数:2
相关论文
共 50 条
  • [21] Identification of cytochrome P450 2E1 in rat brain
    Yoo, M
    Ryu, HM
    Shin, SW
    Yun, CH
    Lee, SC
    Ji, YM
    You, KH
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1997, 231 (02) : 254 - 256
  • [22] Human cytochrome P450 2E1 inhibits cytochrome P450 2B4's activity by competing for cytochrome P450 reductase through a synergistic interaction
    Kenaan, Cesar
    Shea, Erin V.
    Lin, Hsia-lien
    Zhang, Haoming
    Pratt-Hyatt, Matthew
    Hollenberg, Paul F.
    DRUG METABOLISM REVIEWS, 2011, 43 : 62 - 63
  • [23] Functional characterization of human and cynomolgus monkey cytochrome P450 2E1 enzymes
    Hanioka, Nobumitsu
    Yamamoto, Maki
    Iwabu, Hiroyuki
    Jinno, Hideto
    Tanaka-Kagawa, Toshiko
    Naito, Shinsaku
    Shimizu, Takefumi
    Masuda, Kazufumi
    Katsu, Takashi
    Narimatsu, Shizuo
    LIFE SCIENCES, 2007, 81 (19-20) : 1436 - 1445
  • [24] Human cytochrome P450 2E1 is a major autoantigen associated with halothane hepatitis
    Bourdi, M
    Chen, WQ
    Peter, RM
    Martin, JL
    Buters, JTM
    Nelson, SD
    Pohl, LR
    CHEMICAL RESEARCH IN TOXICOLOGY, 1996, 9 (07) : 1159 - 1166
  • [25] Cytochrome P450 4A and 2E1 expression in human kidney microsomes
    Amet, Y
    Berthou, F
    Fournier, G
    Dreano, Y
    Bardou, L
    Cledes, J
    Menez, JF
    BIOCHEMICAL PHARMACOLOGY, 1997, 53 (06) : 765 - 771
  • [26] Inhibition of human cytochrome P450 2E1 by halogenated anilines, phenols, and thiophenols
    Ohashi, Y
    Yamada, K
    Takemoto, I
    Mizutani, T
    Saeki, K
    BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2005, 28 (07) : 1221 - 1223
  • [27] FUNCTIONAL CHARACTERIZATION OF HUMAN AND CYNOMOLGUS MONKEY CYTOCHROME P450 2E1 ENZYMES
    Yamamoto, Maki
    Iwabu, Hiroyuki
    Yonemoto, Rei
    Masuda, Kazufumi
    Katsu, Takashi
    Hanioka, Nobumitsu
    Jinno, Hideto
    Tanaka-Kagawa, Toshiko
    Naito, Shinsaku
    Shimizu, Takefumi
    Narimatsu, Shizuo
    DRUG METABOLISM REVIEWS, 2007, 39 : 112 - 113
  • [28] Differential inhibition of naringenin on human and rat cytochrome P450 2E1 activity
    Santes-Palacios, Rebeca
    Olguin-Reyes, Sitlali
    Luz Hernandez-Ojeda, Sandra
    Camacho-Carranza, Rafael
    Javier Espinosa-Aguirre, Jesus
    TOXICOLOGY IN VITRO, 2020, 69
  • [29] Inhibition of cytochrome P450 2E1 by propofol in human and porcine liver microsomes
    Lejus, C
    Fautrel, A
    Mallédant, Y
    Guillouzo, A
    BIOCHEMICAL PHARMACOLOGY, 2002, 64 (07) : 1151 - 1156
  • [30] Human cytochrome P450 2E1 (CYP2E1): From genotype to phenotype
    Carriere, V
    Berthou, F
    Baird, S
    Belloc, C
    Beaune, P
    deWaziers, I
    PHARMACOGENETICS, 1996, 6 (03): : 203 - 211