A preface on advances in diagnostics for infectious and parasitic diseases: detecting parasites of medical and veterinary importance

被引:5
|
作者
Stothard, J. Russell [1 ]
Adams, Emily [1 ]
机构
[1] Univ Liverpool, Liverpool Sch Trop Med, Dept Parasitol, Liverpool L3 5QA, Merseyside, England
关键词
point-of-contact; microscopy; rapid diagnostic test; qPCR; LAMP; ASSURED; CUTANEOUS LEISHMANIASIS; AMPLIFICATION KIT; GLOBAL BURDEN; MALARIA; TESTS; ELIMINATION; SCHISTOSOMA; SURVEILLANCE; PERFORMANCE; MICROSCOPE;
D O I
10.1017/S0031182014001309
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
There are many reasons why detection of parasites of medical and veterinary importance is vital and where novel diagnostic and surveillance tools are required. From a medical perspective alone, these originate from a desire for better clinical management and rational use of medications. Diagnosis can be at the individual-level, at close to patient settings in testing a clinical suspicion or at the community-level, perhaps in front of a computer screen, in classification of endemic areas and devising appropriate control interventions. Thus diagnostics for parasitic diseases has a broad remit as parasites are not only tied with their definitive hosts but also in some cases with their vectors/intermediate hosts. Application of current diagnostic tools and decision algorithms in sustaining control programmes, or in elimination settings, can be problematic and even ill-fitting. For example in resource-limited settings, are current diagnostic tools sufficiently robust for operational use at scale or are they confounded by on-the-ground realities; are the diagnostic algorithms underlying public health interventions always understood and well-received within communities which are targeted for control? Within this Special Issue (SI) covering a variety of diseases and diagnostic settings some answers are forthcoming. An important theme, however, throughout the SI is to acknowledge that cross-talk and continuous feedback between development and application of diagnostic tests is crucial if they are to be used effectively and appropriately.
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页码:1781 / 1788
页数:8
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