Efficacy of First Line Doxorubicin and Ifosfamide in Primary Cardiac Synovial Sarcoma

Synovial sarcomas are rare entities accounting for less than 1% in all primary cardiac tumors. These tumors are extremely aggressive and generally have a poor prognosis. We report a recent case from Agripa lonescu"Emergency Clinical Hospital Bucharest. A 33-years-old Caucasian male was diagnosed in April 2013 with right ventricle tumor. Histopathological examination indicated a biphasic synovial sarcoma (G3). Both intra-cardiac ventricle tumor and tricuspid valve were removed through surgical atrium-ventricle double approach and tricuspid valve was replaced with biological prosthesis. Post-surgery evolution was favorable, thoracic and abdominal CT scans didn't give evidence of metastasis. The patient received adjuvant chemotherapy with doxorubicin and ifosfamide and was free of disease on regular follow-ups for 16 months.