Novel chitosan derivatives of 2-imidazolecarboxaldehyde and 2-thiophenecarboxaldehyde and their antibacterial activity

被引：26
|
作者：
Yadav, Manoj Kumar [1 ]
Pokhrel, Shanta [2 ]
Yadav, Paras Nath [1 ]
机构：
[1] Tribhuvan Univ, Cent Dept Chem, Kathmandu, Nepal
[2] Tribhuvan Univ, Dept Chem, Trichandra Multiple Campus, Kathmandu, Nepal
来源：
JOURNAL OF MACROMOLECULAR SCIENCE PART A-PURE AND APPLIED CHEMISTRY | 2020年 / 57卷 / 10期
关键词：
Antibacterial activity; chitosan-imidazole; chitosan-thiophene; C-13-NMR spectroscopy; FTIR; TGA; ANTIMICROBIAL ACTIVITY; SCHIFF-BASE; DEACETYLATION; CHITIN; ACETYLATION; WATER; ACID;
D O I：
10.1080/10601325.2020.1763809
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
Chitosan was synthesized from chitin; extracted from prawn shells' powder via deacetylation and physicochemical properties were studied. Novel chitosan derivatives of 2-imidazolecarboxaldehyde and 2-thiophenecarboxaldehyde were synthesized by refluxing equimolar quantities of respective aldehyde with chitosan. These functionalized chitosan derivatives were characterized by Fourier transform infrared (FTIR), C-13-nuclear magnetic resonance (C-13-NMR) spectroscopy, elemental analysis, X-ray diffraction (XRD), thermogravimetric analysis (TGA) and differential thermal analysis (DTA) and their antibacterial activity was explored. Chitosan derivative of 2-thiophenecarboxaldehyde was found active against Escherichia coli.
引用
收藏
页码：703 / 710
页数：8
相关论文
共 50 条
  • [31] Synthesis of novel acrylyl pyranochromen-2-one derivatives and their antibacterial activity evaluation
    Prasad, Suchita
    Mittal, Ayushi
    Sharma, Sunil K.
    INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 2019, 58 (04): : 482 - 496
  • [32] Synthesis and antibacterial activity of 2,2′-dithiobis(benzamide) derivatives
    Jhaumeer-Laulloo, BS
    INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2000, 9 (03) : 193 - 196
  • [33] Synthesis and antibacterial activity of 2′-deoxy macrolide derivatives
    Melman, Artem
    LeTourneau, Nicolas J.
    Mankin, Alexander
    Klepacki, Dorota
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2012, 244
  • [34] ANTIBACTERIAL ACTIVITY OF 2-ACETYLINDOLE HALOGEN DERIVATIVES
    MALYUGA, OA
    CHELYSHEVA, GM
    LEDENEVA, NA
    KISELEV, VK
    ANANINA, GD
    GORBUNOVA, SM
    GORBUNOV, VI
    KHIMIKO-FARMATSEVTICHESKII ZHURNAL, 1976, 10 (10): : 28 - 30
  • [35] THE ANTIBACTERIAL ACTIVITY OF SIMPLE DERIVATIVES OF 2-AMINOPHENOL
    BARBER, M
    HASLEWOOD, GAD
    BIOCHEMICAL JOURNAL, 1945, 39 (04) : 285 - 287
  • [36] Cytotoxic and antibacterial activity of 2-oxopurine derivatives
    Andresen, G
    Gundersen, LL
    Nissen-Meyer, J
    Rise, F
    Spilsberg, B
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2002, 12 (04) : 567 - 569
  • [37] Synthesis of Selenium-Containing Chitosan Derivatives and Their Antibacterial Activity
    Egorov, A. R.
    Artemjev, A. A.
    Kozyrev, V. A.
    Sikaona, D. N.
    Rubanik, V. V., Jr.
    Kritchenkov, I. S.
    Yagafarov, N. Z.
    Khubiev, O. M.
    Tereshina, T. A.
    Kultyshkina, E. K.
    Medjbour, B.
    Khrustalev, V. N.
    Kritchenkov, A. S.
    APPLIED BIOCHEMISTRY AND MICROBIOLOGY, 2022, 58 (02) : 132 - 135
  • [38] Preparation of water-soluble chitosan derivatives and their antibacterial activity
    Xie, WM
    Xu, PX
    Wang, W
    Liu, Q
    JOURNAL OF APPLIED POLYMER SCIENCE, 2002, 85 (07) : 1357 - 1361
  • [39] Synthesis, characterization and antibacterial activity of new fluorescent chitosan derivatives
    Prichystalova, Hana
    Almonasy, Numan
    Abdel-Mohsen, A. M.
    Abdel-Rahman, Rasha. M.
    Fouda, Moustafa M. G.
    Vojtova, L.
    Kobera, Libor
    Spotz, Zdenek
    Burgert, Ladislav
    Jancar, J.
    INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2014, 65 : 234 - 240
  • [40] Synthesis of chitosan derivatives with quaternary ammonium salt and their antibacterial activity
    Chun Ho Kim
    Jang Won Choi
    Heung Jae Chun
    Kyu Suk Choi
    Polymer Bulletin, 1997, 38 : 387 - 393
12345