Synthesis of thiazolyl benzimidazoles and thiazolyl coumarins linked to isoxazole as possible biodynamic agents

被引：0
|
作者：
Rajanarendar, E. [1 ]
Murthy, K. Rama [1 ]
Reddy, M. Nagi [1 ]
Shaik, Firoz Pasha [1 ]
机构：
[1] Kakatiya Univ, Dept Chem, Warangal 506009, Andhra Pradesh, India
来源：
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY | 2011年 / 50卷 / 11期
关键词：
Cyclocondensation; isoxazolyl thiazolyl-5-acetic acids; benzimidazolyl isoxazolyl thiazolan-4-ones; chromenyl isoxazolyl thiazolan-4-ones; ANTIFUNGAL; DESIGN; ANTIBACTERIAL; INHIBITORS; ISOMERS; AMIDES;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A new series of linked heterocyclics, 5-(1H-benzo[d]imidazo-l2-yl-methyl)-3-(3-methyl-5-[(E)-2-phenyl-1-ethenyl]-4-isoxazolyl)-2-aryl-1,3-thiazolan-4-ones 4 and 3-{3-methyl-5-[(E)-2-phenyl-1-ethenyl]-4-isoxazolyl}-5-(2-oxo-2H-3-chromenyl)-2-aryl-1,3-thiazolan-4-ones 5 have been synthesized by the cyclocondensation of 4-benzalamino-3-methyl-5-styrylisoxazole 2 with mercapto succinic acid followed by cyclization with 1,2-phenylenediamines or salicylaldehydes. Structures of all the newly synthesized compounds 3-5 have been confirmed by spectral and micro analytical data.
引用
收藏
页码：1658 / 1666
页数：9
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