EDP-305, A Novel and Potent Farnesoid X Receptor Agonist, Exhibits Favorable Anti-inflammatory and Anti-fibrotic Activity In Vitro

被引:0
|
作者
Li, Yang [1 ]
Chau, Mary D. [1 ]
Wang, Guoqiang [1 ]
Or, Yat Sun [1 ]
Jiang, Lijuan [1 ]
机构
[1] Enanta Pharmaceut Inc, Watertown, MA USA
关键词
D O I
暂无
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
1596
引用
收藏
页码:791A / 791A
页数:1
相关论文
共 50 条
  • [21] Anti-inflammatory and anti-fibrotic effects of novel peptide GQDGLAGPK in alkaline burns rabbit
    Iin, Lee Yoon
    Lee, Hye Sook
    Lee, YuJin
    Yang, JaeWook
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2016, 57 (12)
  • [22] Novel Anti-inflammatory and Anti-fibrotic Agents for Diabetic Kidney Disease-From Bench to Bedside
    Nicholas, Susanne B.
    ADVANCES IN CHRONIC KIDNEY DISEASE, 2021, 28 (04) : 378 - 390
  • [23] A pilot study of a novel anti-inflammatory and anti-fibrotic agent, pirfenidone, in patients with liver cirrhosis.
    Armendariz-Borunda, J
    Islas-Carbajal, MC
    Meza, E
    Rincon, AR
    Alvarez, A
    Goodman, ZD
    Sandoval, A
    Covarrubias, A
    Arechiga, G
    Garcia, L
    HEPATOLOGY, 2003, 38 (04) : 308A - 308A
  • [24] Direct angiotensin AT2 receptor stimulation by the novel non-peptide agonist Compound 21 acts anti-inflammatory and anti-fibrotic in a mouse model of scleroderma
    Stroeder, K.
    Rompe, F.
    Reichenbach, A.
    Thoene-Reineke, C.
    Artuc, M.
    Hallberg, A.
    Alterman, M.
    Unger, T.
    Steckelings, U. M.
    JOURNAL OF HYPERTENSION, 2008, 26 : S369 - S369
  • [25] Anti-fibrotic and anti-inflammatory effect of a novel LPA1 receptor antagonist, UD-009, in a mouse model of NASH
    Nishikawa, Kenji
    Nonouchi, Shimpei
    Okanari, Eiji
    Shinohara, Yuuko
    Nishida, Hiroshi
    Iwase, Noriaki
    Tokunaga, Yasunori
    Ushiyama, Shigeru
    HEPATOLOGY, 2016, 64 : 831A - 831A
  • [26] Anti-fibrotic and anti-inflammatory activity of the adenosine receptor 2b antagonist, GS-6201, in a murine model of PSC
    Karnik, Satyajit
    Kim, Yong Ook
    Nash, Michelle
    Sulfab, Maisoun
    Zeng, Dewan
    Zhong, Hongyan
    Robson, Simon C.
    Schuppan, Detlef
    Tumas, Daniel
    HEPATOLOGY, 2014, 60 : 576A - 577A
  • [27] Icosabutate, a Novel Structurally Engineered Fatty-Acid, Exhibits Potent Anti-Inflammatory and Anti-Fibrotic Effects in a Dietary Mouse Model Resembling Progressive Human Non-Alcoholic Steatohepatitis
    Fraser, David
    Wang, Xiaoyu
    Skjaeret, Tore
    Schuppan, Detlef
    HEPATOLOGY, 2018, 68 : 749A - 750A
  • [28] The Novel AT2 Receptor Agonist β-Pro7-AngIII Exerts Cardiac and Renal Anti-Fibrotic and Anti-Inflammatory Effects in High Salt-Fed Mice
    Wang, Yan
    Yodgee, Jonathan
    Del Borgo, Mark
    Spizzo, Iresha
    Nguyen, Levi
    Aguilar, Marie-Isabel
    Denton, Kate M.
    Samuel, Chrishan S.
    Widdop, Robert E.
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 23 (22)
  • [29] Identification of a Potent, Selective, and Structurally Novel GPR120 Agonist with Anti-inflammatory Activity
    Kim, Byung Gyu
    DIABETES, 2015, 64 : A321 - A322
  • [30] Late Breaking Abstract - Anti-fibrotic and anti-inflammatory properties of isoform-selective SIK inhibitors in vitro and in vivo
    Wiqvist, Kristin
    Vidal, Alexander
    Ingelsten, Madeleine
    Ottosson, Tomas
    Gurcan, Eylem
    Markou, Thomais
    Goransson, Melker
    EUROPEAN RESPIRATORY JOURNAL, 2023, 62