Monoolein cubic phase containing poly(hydroxyethyl acrylate-co-propyl methacrylate-co-methacrylic acid) and its electric field-driven release property

被引:12
|
作者
Park, Seok Ho [1 ]
Kim, Jin-Chul [1 ]
机构
[1] Kangwon Natl Univ, Coll Biomed Sci, Dept Med Biomat Engn, 192-1,Hyoja 2 Dong, Chunchon 200701, Kangwon Do, South Korea
关键词
Monoolein; Cubic phase; Ionic copolymer; Amaranth; Electric field-driven release; 2-HYDROXYETHYL ACRYLATE; COPOLYMERS; KINETICS; LAMELLAR;
D O I
10.1016/j.jiec.2018.10.019
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Monoolein cubic phase containing poly(hydroxyethyl acrylate-co-propyl methacrylate-co-methacrylic acid) was prepared by a melt-hydration method. The electric field (1.5 V, 3 V, and 4.5 V) promoted the release of amaranth (a negatively charged dye) loaded in the cubic phase. The release degree of the dye loaded in the cubic phase without the copolymer increased in a saturation manner with increasing the voltage intensity. Meanwhile, the release degree in presence of the copolymer increased in a gradual manner with the voltage intensity. The electric field-driven release was promoted more when the content of methacrylic acid unit of the copolymer was higher. (C) 2018 The Korean Society of Industrial and Engineering Chemistry. Published by Elsevier B.V. All rights reserved.
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页码:226 / 233
页数:8
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