Head and neck squamous cell carcinoma express receptors for PGE2 and bradykinin that transactivate the EGFR signaling axis increasing tumor invasion and proliferation

被引：0
|
作者：
Thomas, Sufi M.
Zhang, Qing
Kalyankrishna, Shailaja
Wentzel, Abbey
Freilino, Maria
Gubish, Chris
Gooding, William E.
Siegfried, Jill M.
Chan, Daniel C.
Grandis, Jennifer R.
机构：
[1] Univ Pittsburgh, Pittsburgh, PA USA
[2] Univ Colorado, Hlth Sci Ctr, Denver, CO USA
来源：
CANCER RESEARCH | 2006年 / 66卷 / 08期
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
4819
引用
收藏
页数：2
相关论文
共 50 条
  • [21] VAV2 signaling promotes regenerative proliferation in both cutaneous and head and neck squamous cell carcinoma
    L. Francisco Lorenzo-Martín
    Natalia Fernández-Parejo
    Mauricio Menacho-Márquez
    Sonia Rodríguez-Fdez
    Javier Robles-Valero
    Sonia Zumalave
    Salvatore Fabbiano
    Gloria Pascual
    Juana M. García-Pedrero
    Antonio Abad
    María C. García-Macías
    Nazareno González
    Pablo Lorenzano-Menna
    Miguel A. Pavón
    Rogelio González-Sarmiento
    Carmen Segrelles
    Jesús M. Paramio
    José M. C. Tubío
    Juan P. Rodrigo
    Salvador A. Benitah
    Myriam Cuadrado
    Xosé R. Bustelo
    Nature Communications, 11
  • [22] In vitro expression of genes encoding HIF1α, VEGFA, PGE2 synthases, and PGE2 receptors in feline oral squamous cell carcinoma
    Nasry, Walaa Hamed Shaker
    Rodriguez-Lecompte, Juan Carlos
    Martin, Chelsea K.
    JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION, 2025, 37 (02) : 223 - 233
  • [23] P2Y2 receptors mediate nucleotide-induced EGFR phosphorylation and stimulate proliferation and tumorigenesis of head and neck squamous cell carcinoma cell lines
    Woods, Lucas T.
    Jasmer, Kimberly J.
    Forti, Kevin Munoz
    Shanbhag, Vinit C.
    Camden, Jean M.
    Erb, Laurie
    Petris, Michael J.
    Weisman, Gary A.
    ORAL ONCOLOGY, 2020, 109
  • [24] Rab 18 Regulates Proliferation, Invasion and Cisplatin Sensitivity Through STAT3 Signaling in Head and Neck Squamous Cell Carcinoma
    Ji, Xu
    Guo, Xing
    Wang, Yan
    Li, Xiaotian
    Li, Hong
    ONCOTARGETS AND THERAPY, 2020, 13 : 4123 - 4134
  • [25] Inhibition of β-catenin/CBP signaling alters EGFR fucosylation status in head and neck squamous cell carcinoma
    Chandler, Kevin B.
    Alamoud, Khalid
    Bac-Cuc Nguyen
    Stahl, Vanessa L.
    Owa, Takashi
    Nomoto, Kenichi
    Monti, Stefano
    Kukuruzinska, Maria A.
    Costello, Catherine E.
    CANCER RESEARCH, 2020, 80 (16)
  • [26] COX-2-mediated PGE2 activates EGFR and Met receptor and induces hepatocellular carcinoma cell invasion
    Han, C
    Demetris, AJ
    Michalopoulos, GK
    Wu, T
    FASEB JOURNAL, 2005, 19 (05): : A1049 - A1049
  • [27] HOXB5 acts as an oncogenic driver in head and neck squamous cell carcinoma via EGFR/Akt/Wnt/β-catenin signaling axis
    Lee, Kyungmin
    Chang, Jae Won
    Oh, Chan
    Liu, Lihua
    Jung, Seung-Nam
    Won, Ho-Ryun
    Kim, Young Il
    Rha, Ki-Sang
    Koo, Bon Seok
    EJSO, 2020, 46 (06): : 1066 - 1073
  • [28] Roles of the HGF/Met signaling in head and neck squamous cell carcinoma: Focus on tumor immunity
    Liu, Dongjuan
    Zhong, Ming
    Zhan, Desong
    Zhang, Ying
    Liu, Sai
    ONCOLOGY REPORTS, 2020, 44 (06) : 2337 - 2344
  • [29] FUT6 inhibits the proliferation, migration, invasion, and EGF-induced EMT of head and neck squamous cell carcinoma (HNSCC) by regulating EGFR/ERK/STAT signaling pathway
    Wang, Qian
    Liao, Chengcheng
    Tan, Zhangxue
    Li, Xiaolan
    Guan, Xiaoyan
    Li, Hao
    Tian, Zhongjia
    Liu, Jianguo
    An, Jiaxing
    CANCER GENE THERAPY, 2023, 30 (01) : 182 - 191
  • [30] Head and neck squamous carcinoma cell lines exhibit an intact EGFR signaling pathway and variable response to EGFR agonist and antagonist
    Wong, S.
    Springer, J.
    Fox, D.
    Venkatesan, N.
    Head, C.
    EJC SUPPLEMENTS, 2006, 4 (12): : 182 - 182
12345